Evidence map›Paper›PMID 42050105›Full record

ArticleCommunications biology2026

Graphene quantum dot-coated mesoporous silica loaded with glucosamine sulfate as a potent antigen delivery system for immunoactivation.

Qiran Wang, Shuyao Yang, Yao Wang, Hangyu Li, Yuanzuo Li, Xihui Du, Qian Yang, Fengyuan Wang, Haibo Feng

Abstract read
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qiran Wang *College of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Shuyao Yang *College of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Yao WangCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Hangyu LiCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Yuanzuo LiCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Xihui DuCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Qian YangCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China.
Fengyuan WangCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China. wfy_sccd@163.com.ORCID http://orcid.org/0000-0003-2373-0316
Haibo FengCollege of Animal Science and Veterinary Medicine, Southwest Minzu University, Chengdu, P. R. China. fenghaiborc@126.com.ORCID http://orcid.org/0000-0003-1106-7588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene quantum dots (GQDs) belong to the carbon quantum dot family, with low toxicity, high biocompatibility, and excellent colloidal stability. Mesoporous silica nanoparticles (MSNs) are recognized as effective drug delivery systems due to their high drug-loading capacity, while glucosamine sulfate (GS) exhibits immunemodulatory properties. In this study, to maximize the immune effect of GS, a graphene quantum dot-coated mesoporous silica loaded with glucosamine sulfate (MSN-G-Q) is synthesized, and its immunoactivation effects are evaluated in vitro and in vivo. In vitro, MSN-G-Q enhances macrophage uptake activity, stimulates nitric oxide (NO) production, and upregulates CD80

Indexed as

AntigensDrug Delivery SystemsGlucosamineGraphiteQuantum DotsSilicon DioxideAnimalsCarbon Quantum DotsCytokinesDendritic CellsMiceNanoparticlesOvalbuminPorosityT-LymphocytesAntigensCytokinesGlucosamineGraphiteOvalbuminSilicon Dioxide

Identifiers

PMID42050105
PMCPMC13334014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.