Evidence map›Paper›PMID 42049885›Full record

ArticleScientific reports2026

Investigating the potential of Ulva rigida extracts as a natural anti-aging agent in cosmetics.

Korawinwich Boonpisuttinant, Thanachai Taka, Jantana Praiboon, Saranrat Phuangborisut, Nipaporn Kangkawisut, Warintorn Ruksiriwanich, Romchat Chutoprapat, Wirinda Chompoo, Kitrawi Samothai, Sarinporn Udompong and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Korawinwich BoonpisuttinantInnovative Natural Products From Thai Wisdoms (INPTW), Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi (RMUTT), Pathumthani, 12130, Thailand.
Thanachai TakaiCell Research Institute Laboratory Unit, Bangkok, 10230, Thailand.
Jantana PraiboonDepartment of Fishery Biology, Biology of Fisheries, Kasetsart University, Chatuchak, Bangkok, Thailand.
Saranrat PhuangborisutDepartment of Food Innovation and Business, Faculty of Agro-Industrial Technology, Rajamangala University of Technology Tawan-Ok, Chanthaburi Campus, Chanthaburi, 22210, Thailand.
Nipaporn KangkawisutDepartment of Food Innovation and Business, Faculty of Agro-Industrial Technology, Rajamangala University of Technology Tawan-Ok, Chanthaburi Campus, Chanthaburi, 22210, Thailand.
Warintorn RuksiriwanichDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand.
Romchat ChutoprapatDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Wirinda ChompooInnovative Natural Products From Thai Wisdoms (INPTW), Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi (RMUTT), Pathumthani, 12130, Thailand.
Kitrawi SamothaiInnovative Natural Products From Thai Wisdoms (INPTW), Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi (RMUTT), Pathumthani, 12130, Thailand.
Sarinporn UdompongOffice of the Cane and Sugar Board, Ministry of Industry, Bangkok, Thailand.
Kulwara PoolpolFaculty of Allied Health Sciences, Burapha University, Chonburi, 20131, Thailand. kulwara@go.buu.ac.th.

Funding

the National Research Council of Thailand (NRCT), Thailand Science Research and Innovation Promotion Funding (TSRI) FRB67E1209
6 · The paper itself

Abstract

Based on the study, extracts from sea lettuce (Ulva rigida) or UR show significant promise as a natural anti-aging ingredient for skincare products. The research, conducted on specimens from Phetchaburi, Thailand, compared three extraction methods: juice squeezing (J), boiling (B), and maceration (M) by using 95% ethanol. The results demonstrated that these extracts contain beneficial compounds like phenolics and flavonoids, including rutin, catechin, and quercetin, which contribute to their biological properties. Furthermore, all extracts (UR-J, UR-B, and UR-M) exhibited powerful anti-aging effects. Specifically, the UR-M extracts effectively inhibited anti-melanogenesis activity (5.88 ± 1.25%) and the tyrosinase activity (IC

Indexed as

CosmeticsPlant ExtractsSkin AgingUlvaAnimalsEdible SeaweedsFlavonoidsHumansPhenolsCosmeticsFlavonoidsPhenolsPlant ExtractsBioactivityCytotoxicityNatural productsPhytochemicalsSea lettuce

Identifiers

PMID42049885
PMCPMC13315838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.