Evidence map›Paper›PMID 42049722›Full record

Observational studyNature communications2026

Impacts of jaw surgery on speech in Class III patients.

Erika Rezende Silva, Christine Sirna Bode, Griffin Lowry, Jeannene Matthews, Thao Quynh Ngo, Ayumi Shoji, Jialiu Xie, Aliha Younus, Chelsea D'Abreo, Timothy Turvey and 5 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Erika Rezende Silva *Department of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-9059-1013
Christine Sirna Bode *Department of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Griffin Lowry *Department of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jeannene MatthewsDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Thao Quynh NgoDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ayumi ShojiDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jialiu XieDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-0560-7982
Aliha YounusDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Chelsea D'AbreoDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Timothy TurveyDepartment of Oral and Maxillofacial Surgery, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
George BlakeyDepartment of Oral and Maxillofacial Surgery, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ray WhiteDepartment of Oral and Maxillofacial Surgery, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
David ZajacCraniofacial Center, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jeff MielkeDepartment of English, North Carolina State University, Raleigh, NC, USA.ORCID http://orcid.org/0009-0002-9882-8254
Laura Anne JacoxDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. LJacox@live.unc.edu.ORCID http://orcid.org/0000-0003-1923-6825

Funding

Orthognathic speech pathology: Understanding how jaw disharmonies and their surgical correction influence speechK08DE030235 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACOX, LAURA ANNE · 2021 to 2025
$889k
NIDCR NIH HHS K08 DE030235
6 · The paper itself

Abstract

Patients with severe Dentofacial Disharmony such as Class III underbites have a twentyfold increased prevalence of speech disorders. To understand the longitudinal effects of corrective jaw surgery on speech, a prospective observational cohort study was conducted of Class III patients (n = 67, Ages 15-36, without clefts). Class I proportional controls (n = 54) and Class III patients were recorded 1-2 months pre-surgery, 2-6 months post-surgery (short-term) and 9-14 months post-surgery (long-term). Speech recordings were evaluated through distortion ratings and measurement of spectral changes in consonant production. ANOVAs and linear mixed-effects models were used to assess changes in speech and cephalometric measures. Here we show that spectral features, distortion, self-reported speech outcomes, and cephalometric measures significantly improve post-operatively. Patients with severe distortions improve the most after surgery. Consonant production requires properly positioned articulatory structures, and surgery provides longitudinal speech improvement for patients with jaw disproportions. Data indicate functional benefit of jaw surgery on speech.

Indexed as

JawMalocclusion, Angle Class IIISpeechSpeech DisordersAdolescentAdultCephalometryFemaleHumansMaleProspective StudiesTreatment OutcomeYoung Adult

Identifiers

PMID42049722
PMCPMC13333914

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.