Evidence map›Paper›PMID 42049642›Full record

ArticleThe Laryngoscope2026

Diagnosis and Treatment of Refractory Chronic Cough: An American Broncho-Esophagological Association Expert Consensus Statement.

Ronit E Malka, Anirudh Saraswathula, Gabriela Lilly, Marisa A Ryan, Andrew Bowen, Kenneth W Altman, Milan Amin, Laura Matrka, Ashli K O'Rourke, C Blake Simpson and 4 more

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ronit E MalkaDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-9864-2698
Anirudh SaraswathulaDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gabriela LillyDepartment of Otolaryngology - Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA.
Marisa A RyanDepartment of Otolaryngology - Head and Neck Surgery, University of Utah Health, Salt Lake City, Utah, USA.ORCID https://orcid.org/0000-0001-6987-4441
Andrew BowenMetroHealth Medical Center, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-6542-7932
Kenneth W AltmanDepartment of Otolaryngology - Head & Neck Surgery, Geisinger Medical Center, Danville, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6290-3331
Milan AminDepartment of Otolaryngology - Head and Neck Surgery, New York University School of Medicine, New York, New York, USA.ORCID https://orcid.org/0000-0002-6992-3212
Laura MatrkaDepartment of Otolaryngology - Head and Neck Surgery, The Ohio State University Wexner Medical Center, Eye and Ear Institute, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-9558-5202
Ashli K O'RourkeDepartment of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0002-1293-501X
C Blake SimpsonDepartment of Otolaryngology - Head and Neck Surgery, University of Alabama, Birmingham, Alabama, USA.
Jonathan BockDepartment of Otolaryngology & Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID https://orcid.org/0000-0002-4367-7527
Paul C BrysonSection of Laryngology, Cleveland Clinic Voice Center, Cleveland, Ohio, USA.
Thomas L CarrollDepartment of Otolaryngology - Head and Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-5666-2482
Lee M AkstDepartment of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-8925-0545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop an expert consensus statement (ECS) on the diagnosis and treatment of refractory chronic cough (RCC) in adults. RCC was defined as cough lasting longer than 8 weeks and refractory to standard management of pulmonary, gastrointestinal, sinonasal, and medication-induced etiologies.

methodsAn expert panel of otolaryngologists used published consensus statement methodology to develop statements guiding the diagnosis and management of RCC from an otolaryngologic perspective. A modified Delphi method was used to iteratively select, eliminate, and refine statements based upon accepted methodology until consensus was achieved.

resultsThree iterative Delphi surveys were performed with discussion rounds between each of the voting sessions. Twenty-seven statements met consensus while six statements did not. The clinical statements were grouped into 9 categories: operational definition, pathophysiology, assessment of prior work-up, phenomenology and symptomatology, four treatment categories (neuromodulators, superior laryngeal nerve blocks, behavioral cough suppression, and emerging treatments), and overall treatment approaches.

conclusionThe panel reached consensus for 27 statements related to the diagnosis and treatment of adults with RCC from an otolaryngologic perspective. These statements may be used to standardize evaluation and improve quality of care, while also identifying areas for future investigation in the management of RCC.

Indexed as

Chronic CoughCoughAdultDelphi TechniqueHumansUnited Stateschronic coughchronic cough treatmentcough hypersensitivityidiopathic coughirritable larynxlaryngeal hypersensitivitylaryngopharyngeal refluxmulti‐disciplinary cough managementneurogenic coughSLN block

Identifiers

PMID42049642
PMCPMC13460546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.