Evidence map›Paper›PMID 42049449›Full record

ReviewIn vivo (Athens, Greece)

Pain in Children With ADHD: Mechanisms, Clinical Presentation, and Implications for Assessment and Management.

Maria Rosaria Muzio, Alessandro Vittori, Teresa Grimaldi Capitello, Dalila Esposito, Maria Pia Bruno, Valentina Cerrone, Marco Cascella

Abstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Rosaria MuzioDivision of Infantile Neuropsychiatry, UOMI-Maternal and Infant Health, ASL NA3 SUD Torre del Greco, Naples, Italy.
Alessandro VittoriDepartment of Anesthesia, Critical Care and Pain Medicine, ARCO, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy; alexvittori82@gmail.com.
Teresa Grimaldi CapitelloDepartment of Neuroscience, Clinical Psychology Unit, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy.
Dalila EspositoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Maria Pia BrunoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Valentina CerroneDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Marco CascellaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPain assessment and management in children remain challenging, particularly in those with neurodevelopmental disorders. Attention-deficit/hyperactivity disorder (ADHD) is characterized by alterations in attention, executive function, emotional regulation, and reward processing. These domains are also critically involved in pain perception and expression. Emerging evidence suggests that children with ADHD may experience pain differently, display atypical pain behaviors, and face substantial challenges in pain assessment and treatment. However, the literature on pediatric ADHD and pain is fragmented across experimental, clinical, and behavioral studies. MATERIALS AND

methodsThis narrative review critically examines the neurobiological, psychological, and clinical interactions between ADHD and pain in children.

resultsWe discuss proposed mechanisms linking ADHD to altered pain processing, summarize evidence on pain perception and expression, explore common pain conditions where this interaction is clinically relevant, and analyze challenges in pain assessment and management. Finally, we identify knowledge gaps and propose future directions toward function- and child-centered pain care.

conclusionBy considering ADHD as a modifier of pain experience and a potential contributor to pain chronification rather than a mere comorbidity, this review highlights the importance of adapting pain assessment and management strategies to the specific neurodevelopmental profile of pediatric patients.

Indexed as

Attention Deficit Disorder with HyperactivityPainChildHumansPain ManagementPain Measurementattention-deficit/hyperactivity disorderchildrenPainreview

Identifiers

PMID42049449
PMCPMC13133816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.