Evidence map›Paper›PMID 42049406›Full record

ArticleIn vivo (Athens, Greece)

Exercise Stimulates

Sermin Durak, Saadet Busra Aksoyer Sezgin, Faruk Celik, Yasemin Yilmazer, Aydin Cevik, Ozlem Kucukhuseyin, Ilhan Yaylim, Umit Zeybek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sermin DurakDepartment of Medical Microbiology, Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Saadet Busra Aksoyer SezginDepartment of Medical Biology and Genetics, Faculty of Medicine, Istanbul Yeni Yuzyil University, Istanbul, Türkiye.
Faruk CelikDepartment of Medical Genetic, Faculty of Medicine, Alanya Alaaddin Keykubat University, Antalya, Türkiye.
Yasemin YilmazerDeparment of Molecular Biology and Genetics, Istanbul Sabahattin Zaim University, Istanbul, Türkiye.
Aydin CevikDepartment of Molecular Medicine, Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Türkiye.
Ozlem KucukhuseyinDepartment of Molecular Medicine, Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Türkiye.
Ilhan YaylimDepartment of Molecular Medicine, Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Türkiye.
Umit ZeybekDepartment of Molecular Medicine, Institute of Graduate Studies in Health Sciences, Istanbul University, Istanbul, Türkiye zeybekumit67@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAdipose tissue is pivotal in regulating metabolism, functioning not only as an energy store but also as an endocrine organe. Our investigation focused on the gene expression levels of MATERIALS AND

methodsThe study consisted of three groups: control (C), high-fat diet (HFD), and exercise-high fat diet (E-HFD) groups. While HFD and E-HFD mice received a 60% fat diet, controls received a 10% fat diet. Real-time polymerase chain reaction system was applied to evaluate gene expression levels in hepatic, adipose, and heart tissues. Pro-inflammatory cytokine levels in the serum were quantified using ELISA kits according to the protocols.

resultsIn contrast to the control and HFD groups, the E-HFD group exhibited notably elevated gene expressions of

conclusionExercise and high-fat diet intervention significantly alter expression levels of mitophagy-related genes

Indexed as

Autophagy-Related ProteinsDiet, High-FatGene Expression RegulationGTP PhosphohydrolasesMitochondrial ProteinsPhysical Conditioning, AnimalProtein KinasesUbiquitin-Protein LigasesAdipose TissueAnimalsLiverMaleMiceMice, Inbred C57BLObesityOrgan SpecificityAutophagy-Related ProteinsGTP PhosphohydrolasesMfn1 protein, mouseMitochondrial Proteinsparkin proteinProtein KinasesPTEN-Induced Putative KinaseUbiquitin-Protein LigasesATG-3MFN-1ObesityPARKINPINK-1

Identifiers

PMID42049406
PMCPMC13133826

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.