ArticleInternational dental journal2026
Effect of Apical Micro-Intervention on Pulp Vitality and Periodontal Regeneration Following Tooth Autotransplantation: A Clinical Outcome Study.
Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the effects of different root apex preparation methods on pulp revascularization and periodontal regeneration after autologous tooth transplantation.
methodsUsing 64 anterior teeth from 6 male Beagle dogs, we compared natural socket preservation (retaining periodontal ligament/PDL) versus artificial socket preparation, with subgroups receiving: (1) circumferential 2 mm apex PDL removal (Cpr), (2) 3 mm apical resection+iRoot BP retrofilling (ArrN/ArrA), (3) apical foramen enlargement >1 mm (Afe), (4) immediate root canal treatment (RCTN/RCTA), or (5) no treatment (ControlA/ControlN). Contralateral autotransplantation of teeth was performed, followed by 6 months of clinical and radiographic monitoring prior to micro-CT and histological analysis.
resultsThe natural socket group showed superior outcomes, with significantly lower probing depths (P < .05) and better survival rates. Radiographic and Micro-CT revealed severe root resorption in Controls and ArrN groups, while ArrA/Cpr groups exhibited reduced apical radiolucency. Notably, high-density intracanal deposits in ArrN/ArrA suggested pulp regeneration, whereas Afe specimens displayed osteoid-like pulp deposits. Histologically, Controls developed discontinuous PDL (Periodontal ligament), extensive resorption and fibrous tissue thickening, while treated teeth maintained better periodontal integrity. These findings demonstrate that PDL preservation combined with apical sealing (particularly ArrN/ArrA protocols) significantly enhances transplantation success by: (1) maintaining apical vascularity, (2) preventing inflammatory resorption through hermetic sealing, and (3) facilitating stem cell recruitment.
conclusionIn tooth autotransplantation, maximal preservation of periodontal ligament cells within the recipient socket helps reduce postoperative root resorption and periodontal inflammation. Sealing the donor tooth apex, whether by intraoperative apical resection-retrofilling or postoperative root canal treatment, effectively controls apical inflammation and improves the success rate of transplantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.