Evidence map›Paper›PMID 42048609›Full record

ArticleEpigenetics2026

Zhaohui Zhang, Aibuta Yeerken, Xinyao Shao, Sangni Qian, Shujuan Lin, Simeng Gu, Xiaojiang Ying, Zhenjun Li, Xinglin Fei, Jinhua Yang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhaohui ZhangDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Aibuta YeerkenDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xinyao ShaoDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Sangni QianDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Shujuan LinDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Simeng GuDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiaojiang YingDepartment of Anorectal Surgery, Shaoxing People's Hospital, Shaoxing, China.
Zhenjun LiDepartment of Anorectal Surgery, Shaoxing People's Hospital, Shaoxing, China.
Xinglin FeiJiashan Institute of Cancer Prevention and Treatment, Jiaxing, China.
Jinhua YangJiashan Institute of Cancer Prevention and Treatment, Jiaxing, China.
Mengling TangDepartment of Public Health, Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jianbing WangDepartment of Public Health, National Clinical Research Center for Child Health of the Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Mingjuan JinDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0003-2358-0186
Kun ChenDepartment of Public Health, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Although epigenetic alterations are common in CRC, the epigenetic changes that occur during colorectal carcinogenesis remain unclear. Thus, we sought to elucidate the role of

Indexed as

AdenomaColorectal NeoplasmsDNA MethylationNitric Oxide Synthase Type IEpigenesis, GeneticFemaleGene Expression Regulation, NeoplasticHumansMalePrognosisPromoter Regions, GeneticNitric Oxide Synthase Type INOS1 protein, humancarcinogenesiscolorectal adenomaColorectal cancerDNA methylationNOS1

Identifiers

PMID42048609
PMCPMC13128025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.