Evidence map›Paper›PMID 42048303›Full record

ArticleNephron2026

Rhabdomyolysis and Acute Kidney Injury after the New York City Marathon.

Jordan L Rosenstock, Douglas R Farrell, Steven G Coca, Salman Millwala, Sahar Mahani, Miriam Chung, Jamie Hirsch, Lili Chan, Pooja A Gownivaripally, Gregg Husk and 2 more

Abstract read
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In one paragraph

Article in Nephron, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jordan L RosenstockDivision of Nephrology, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, New York, New York, USA.
Douglas R FarrellDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA, douglas.farrell@mountsinai.org.
Steven G CocaDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Salman MillwalaDivision of Nephrology, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, New York, New York, USA.
Sahar MahaniDivision of Nephrology, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, New York, New York, USA.
Miriam ChungDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Jamie HirschDivision of Kidney Diseases and Hypertension, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, New York, USA.
Lili ChanDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Pooja A GownivaripallyDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Gregg HuskMedical Informatics, Lenox Hill Hospital, Northwell Health, New York, New York, USA.
Maria V DeVitaDivision of Nephrology, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, New York, New York, USA.
Tonia KimDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Background: The 2022 NYC Marathon was the hottest on record. At several hospitals near the race's finish, a larger volume of heat stress-related kidney injury was observed. We sought to examine the incidence of post-marathon rhabdomyolysis observed with respect to race day temperature and humidity.

methodsAll charts of patients who had a creatine phosphokinase (CPK) level >5,000 U/L on the date of the marathon and subsequent 4 days for the years 2017-2023 at four NYC hospitals were reviewed. Patients were included for analysis if marathon participation was indicated in the chart and no other causes of rhabdomyolysis were evident. Race day heat was measured as heat index to capture the effects of both temperature and humidity.

resultsIn 2022, there were 24 runners with post-marathon rhabdomyolysis, compared to 15 total patients for the other 5 marathons combined. Cases of post-marathon rhabdomyolysis strongly correlated to race day heat index. In addition to record heat, the 2022 NYC Marathon had the largest change in heat as compared to the previous 14-day average. The 2022 cohort skewed male (20 male: 4 female), was on average 32.2 years of age, and presented within 2 days of the marathon. The average peak CPK was 21,426 IU/L (range 5,177 to 88,430 IU/L). All patients received intravenous fluids. Only 1 patient had a further rise in creatinine, reaching a peak of 8.69 mg/dL (from 5.81 on arrival) before starting hemodialysis.

conclusionThe 2022 NYC Marathon was the hottest on record, and was found to have the highest incidence of post-marathon rhabdomyolysis. Cases of rhabdomyolysis correlated with the race day heat index. Additionally, 2022 had the largest change in race day temperature, which may present an additional risk. </p>.

Indexed as

Acute Kidney InjuryMarathon RunningRhabdomyolysisAdultCreatine KinaseFemaleHumansHumidityIncidenceMaleNew York CityRetrospective StudiesRunningCreatine KinaseAcute kidney injuryClimate changeHeatstrokeRhabdomyolysis

Identifiers

PMID42048303
PMCPMC13299126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.