Evidence map›Paper›PMID 42048264›Full record

ArticleEuropean addiction research2026

Factors Influencing the Prognostic Assessment of Patients with End-Stage Alcohol-Associated Liver Disease before Liver Transplantation.

Phileas Johannes Proskynitopoulos, Verena Regina Käding, Georg Schomerus, Angela Buchholz, Anil Batra, Richard Taubert, Stefan Bleich, Sandra Helen Egbers, Alexander Glahn

Abstract read
In one paragraph

Article in European addiction research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Phileas Johannes ProskynitopoulosDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany, proskynitopoulos.phileas@mh-hannover.de.
Verena Regina KädingDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
Georg SchomerusDepartment of Psychiatry and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.
Angela BuchholzDepartment of Medical Psychology, University Clinic Eppendorf, Hamburg, Germany.
Anil BatraDepartment of Psychiatry and Psychotherapy, University Clinic Tübingen, Tübingen, Germany.
Richard TaubertDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Stefan BleichDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
Sandra Helen EgbersDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
Alexander GlahnDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Although alcohol-associated liver disease (ALD) is a leading cause of liver transplantation, most patients with ALD are never evaluated. This study aims to investigate the prognostic assessment process of medical professionals often involved in treating patients with ALD. We wanted to assess the possible effect of disease understanding, stigmatization, experience in transplantation, and addiction medicine on the liver transplantation evaluation process.

methodsThe study was conducted as an anonymous online survey. In total, 407 health professionals were included in the study (291 medical doctors, 86 nurses, and 30 psychologists). The participants were invited to review five cases of potential liver transplantation candidates and assess the prognostic outcome ("positive control," "negative control," "missing illness insight," "missing social support," "abstinence under 6 months").

resultsMean prognostic assessment scores were significantly different between the cases, with abstinence under 6 months being graded the highest, followed by lack of social support and lack of disease insight. We fitted a linear regression to model the influence of stigmatization, individual alcohol use, disease understanding, and experience in transplant and addiction medicine on the appraisal of each case. All models were significant (Model 1: R = 0.201, p = 0.005; Model 2: R = 0.312, p < 0.001; Model 3: R = 0.291, p < 0.001; Model 4: R = 0.283, p < 0.001; Model 5: R = 0.285, p < 0.001). All factors had a significant effect on one or more of the cases.

conclusionsThe findings suggest that patient and evaluator characteristics significantly impact the prognostic assessment process of patients with ALD and highlight potential biases when assessing the prognosis. </p>.

Indexed as

End Stage Liver DiseaseLiver Diseases, AlcoholicLiver TransplantationAdultFemaleHumansMaleMiddle AgedPrognosisSocial SupportSurveys and QuestionnairesAlcohol-associated liver diseaseAlcohol use disorderStigmatization

Identifiers

PMID42048264
PMCPMC13336762

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.