Evidence map›Paper›PMID 42047948›Full record

ReviewSpine deformity2026

Osteoporosis and adult spinal deformity-a review for spinal surgeons by the SRS adult spinal deformity task force on senescence.

Elizabeth Lord, Matthew Vincent, Corey T Walker, Joseph Osorio, Camilo Molina, Kristen Jones, Miranda van Hooff, Alekos Theologis, Mitsuru Yagi, Laurel Blakemore and 10 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Elizabeth LordDepartment of Orthopedics, University of California Los Angeles, Los Angeles, CA, US. elord@mednet.ucla.edu.ORCID http://orcid.org/0000-0003-2433-2475
Matthew VincentDepartment of Orthopedics, University of California Los Angeles, Los Angeles, CA, US.
Corey T WalkerDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, US.
Joseph OsorioDepartment of Neurosurgery, University of California San Diego, San Diego, CA, US.
Camilo MolinaDepartment of Neurosurgery, Washington University in St. Louis, St. Louis, MO, US.
Kristen JonesDepartment of Neurosurgery, Duke University, Durham, NC, US.
Miranda van HooffDepartment for Scientific Research, Sint Maartenskliniek, Ubbergen, Nijmegen, Netherlands.
Alekos TheologisDepartment of Orthopedic Surgery, University of California, San Francisco, CA, US.
Mitsuru YagiDepartment of Orthopedic Surgery, International University of Health and Welfare, Tochigi, Japan.
Laurel BlakemoreDepartment of Orthopedic Surgery, Pediatric Specialists of Virginia, Fairfax, VA, US.
Suken ShahDepartment of Orthopedic Surgery, Nemours Children's Hospital, Wilmington, DE, US.
Serena HuDepartment of Orthopedic Surgery, Stanford University, Redwood City, CA, US.
Marinus de
KleuverDepartment of Orthopedic Surgery, Radboud University, Nijmegen, Netherlands.
Javier PizonesDepartment of Orthopedic Surgery, La Paz University Hospital, Madrid, Spain.
Michael KellyDepartment of Orthopedic Surgery, Rady Children's Hospital, San Diego, CA, US.
Ferran PelliseDepartment of Orthopedic Surgery, Barcelona Spine Institute, Barcelona, Spain.
Christopher AmesDepartment of Neurosurgery, University of California San Francisco, San Francisco, CA, US.
Robert EastlackDepartment of Orthopedic Surgery, Scripps Clinics, La Jolla, CA, US.
Scoliosis Research Society Adult Spinal Deformity Task Force Senescence Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the understanding of osteoporosis in the context of adult spinal deformity (ASD) surgery with a focus on diagnosis, surgical risks, non-operative, and operative treatment techniques.

methodsA comprehensive literature search was performed. Articles were identified using the search terms "osteoporosis," "adult spinal deformity," "scoliosis," and "spine surgery." Relevant studies were selected based on their focus on the intersection of these topics with an emphasis on utility in spine surgery.

resultsThis review discusses osteoporosis diagnosis, surgical risks, and non-operative, and surgical treatments in the context of ASD surgery with a focus on clinical applications. Areas for future growth are highlighted.

conclusionAs adult spinal deformity (ASD) patients increase globally, the Scoliosis Research Society (SRS) formed a task force to improve understanding of osteoporosis and its impact on this vulnerable population. This review brings together the latest research on the topic and highlights this area as one of critical importance and growth in the field.

Indexed as

OsteoporosisScoliosisAdultHumansAdult spinal deformityBisphosphonatesOsteopeniaOsteoporosisParathyroid hormone receptor agonists

Identifiers

PMID42047948
PMCPMC13553726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.