Evidence map›Paper›PMID 42047900›Full record

ArticleDiscover oncology2026

Development of the relationship between tumor and mechanobiology over the past 30 years: a bibliometric analysis.

Mengting Jiang, Guoqiao Chen, Jing Yang, Jian Chen, Zhaoqi Shi, Haonan Chen, Hui Lin, Xiaoxiao Fan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengting Jiang *Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China.
Guoqiao Chen *Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China.
Jing YangDepartment of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China.
Jian ChenDepartment of Cardiac Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhaoqi ShiDepartment of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China.
Haonan ChenDepartment of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China.
Hui LinDepartment of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China. 369369@zju.edu.cn.
Xiaoxiao FanDepartment of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Rd, 310016, Hangzhou, China. fanxx_gs@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of mechanical forces on tumour behaviour has garnered increasing attention in recent years, as these forces significantly affect tumour progression.A comprehensive analysis of global research on tumour mechanobiology is presented here, based on 1759 publications from 1994 to 2023. The analysis focuses on the extracellular matrix(ECM), the tumour microenvironment, and commonly used tools like atomic force microscopy(AFM).A comprehensive review of 612 studies reveals the involvement of multiple cancer types and identifies 137 biomolecules across 10 signalling pathways as central to the interaction between mechanical and biological signals. The findings emphasise the critical role of mechanical forces in tumour biology and suggest the potential for leveraging this knowledge to develop targeted cancer therapies.

Indexed as

Bibliometric analysisExtracellular matrixMechanical forcesTumor mechanobiology

Identifiers

PMID42047900
PMCPMC13253899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.