Evidence map›Paper›PMID 42047791›Full record

ArticleAnalytical and bioanalytical chemistry2026

Dispersive micro-solid-phase extraction coupled to UHPLC-Q-TOF-MS and UHPLC-QqQ-MS for suspect and target screening of illicit drugs and pharmaceuticals in wastewater.

Madson M Nascimento, Paulo R R Mesquita, Ricardo L Cunha, André L S da Silva Junior, Gisele O da Rocha, Raildo M de Jesus, Pedro Afonso de P Pereira, Jailson B de Andrade

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madson M NascimentoUniversidade SENAI CIMATEC, Av. Orlando Gomes, 1845 - Piatã, Salvador, BA, 41650-010, Brazil. madchemis89@gmail.com.ORCID http://orcid.org/0000-0003-4405-6519
Paulo R R MesquitaCentro Tecnológico Agropecuário do Estado da Bahia - CETAB, Secretaria da Agricultura, Pecuária, Irrigação, Pesca e Aquicultura - SEAGRI, Av. Milton Santos, 967 - Ondina, Salvador, BA, 40170-110, Brazil.ORCID http://orcid.org/0000-0003-3187-3800
Ricardo L CunhaLaboratório de Toxicologia Forense, Instituto de Análises e Pesquisas Forenses - IAPF, Polícia Científica, São Cristóvão, SE, 49100-000, Brazil.ORCID http://orcid.org/0000-0003-0444-7742
André L S da Silva JuniorUniversidade Estadual de Santa Cruz, Campus Soane Nazaré de Andrade, Rod. Jorge Amado, Km 16 - Salobrinho, Ilhéus, BA, 45662-900, Brazil.ORCID http://orcid.org/0000-0002-8508-7007
Gisele O da RochaUniversidade Federal da Bahia, Instituto de Química, Campus de Ondina, Salvador, BA, 40170-115, Brazil.ORCID http://orcid.org/0000-0002-1847-8745
Raildo M de JesusUniversidade Estadual de Santa Cruz, Campus Soane Nazaré de Andrade, Rod. Jorge Amado, Km 16 - Salobrinho, Ilhéus, BA, 45662-900, Brazil.ORCID http://orcid.org/0000-0001-6366-948X
Pedro Afonso de P PereiraUniversidade Federal da Bahia, Instituto de Química, Campus de Ondina, Salvador, BA, 40170-115, Brazil.ORCID http://orcid.org/0000-0002-2011-4705
Jailson B de AndradeUniversidade SENAI CIMATEC, Av. Orlando Gomes, 1845 - Piatã, Salvador, BA, 41650-010, Brazil.ORCID http://orcid.org/0000-0001-5269-4866

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 402002/2020-2Conselho Nacional de Desenvolvimento Científico e Tecnológico 465497/2014-4Ministério de Ciência, Tecnologia e Inovação do Brasil - MCTI 904399/2020Projeto Kirimurê 442187/2018-1
6 · The paper itself

Abstract

The increasing global consumption of pharmaceuticals and illicit drugs, particularly new psychoactive substances, has resulted in their continuous release into aquatic environments, raising concerns regarding potential adverse effects on ecosystems and human health. In this study, a dispersive micro-solid-phase extraction using customized extraction devices was developed in combination with liquid chromatography-high-resolution mass spectrometry for target and suspect screening, followed by sensitive quantification by liquid chromatography-tandem mass spectrometry. The extraction procedure was optimized using experimental design. Optimal conditions comprised 50 mg of Oasis MCX sorbent, 100 mL of sample (pH 2, containing 7.5% NaCl, w v⁻

Indexed as

Illicit DrugsLiquid Chromatography-Mass SpectrometrySolid Phase MicroextractionWastewaterWater Pollutants, ChemicalChromatography, High Pressure LiquidLimit of DetectionPharmaceutical PreparationsSolid Phase ExtractionTandem Mass SpectrometryIllicit DrugsPharmaceutical PreparationsWastewaterWater Pollutants, ChemicalD-µ-SPEEnvironmental pollutionIllicit drugsMass spectrometryNew psychoactive substances

Identifiers

PMID42047791
PMCPMC13264539

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.