Evidence map›Paper›PMID 42047749›Full record

ReviewDermatologie (Heidelberg, Germany)2026

[Biologics and infections: understand and recognize].

Galina Balakirski, Pietro Nenoff

Abstract readReviewEnglish Abstract
PubMed Publisher
In one paragraph

Review in Dermatologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Galina BalakirskiZentrum für Dermatologie, Allergologie und Dermatochirurgie, Helios Universitätsklinikum Wuppertal, Universität Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Deutschland. galina.balakirski@helios-gesundheit.de.
Pietro NenoffPartnerschaft Dr. Michael Gerber, Prof. Frank Bühling, Prof. Pietro Nenoff, Tobias Löwe, Erik von Rein, Labor Leipzig-Mölbis, labopart - Medizinische Laboratorien, Mölbiser Hauptstr. 8, 04571, Rötha/OT Mölbis, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is now impossible to imagine dermatology without the use of biologics. The numerous substances approved for the treatment of chronic inflammatory skin diseases in recent decades have become an integral part of dermatological treatment plans. Severe chronic inflammatory dermatoses such as psoriasis vulgaris, atopic dermatitis, and hidradenitis suppurativa can be significantly relieved using these therapeutics. The specific inhibition of important immunological pathways leads to a decrease in disease activity, but the reduction of particular proinflammatory cytokines may also impair the immune response and increase susceptibility to infections. For example, systemic therapy with tumor necrosis factor-alpha (TNF-α) inhibitors can lead to the reactivation of latent tuberculosis infection, and the use of interleukin (IL)-17 blockers has been associated with an increase in candida infections of the skin and mucous membranes. This article presents an overview of possible infection complications during systemic therapy with biologics.

Indexed as

Biological ProductsSkin DiseasesHumansTumor Necrosis Factor-alphaBiological ProductsTumor Necrosis Factor-alphaAtopic dermatitisCandida infectionsHerpes zosterLupus erythematosusPsoriasis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.