Evidence map›Paper›PMID 42047723›Full record

ArticleBulletin of experimental biology and medicine2026

Tumor Cell Lines as a Biosensor Substrate for Pathological Aging and CNS Tumors.

V V Kudelkina, A M Kosyreva, E A Miroshnichenko

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

V V KudelkinaPetrovsky National Research Center of Surgery, Avtsyn Research Institute of Human Morphology, Moscow, Russia. verakudelkina8047@gmail.com.
A M KosyrevaPetrovsky National Research Center of Surgery, Avtsyn Research Institute of Human Morphology, Moscow, Russia.
E A MiroshnichenkoPetrovsky National Research Center of Surgery, Avtsyn Research Institute of Human Morphology, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary screening of the sera from aging Wistar rats and animals with high-grade gliomas was performed using the following cell lines: Gasser's node neuroma (NGUK, trigeminal schwannoma) and high-grade glioma 11-9-2. Targeted analysis of the transcripts of the marker genes S100b (involved in nervous system homeostasis and damage), Sox2 (stemness marker), and Mki67 (proliferation marker), along with mitotic cell counting revealed statistically significant differences in transcriptional activity between the groups. This initial assessment of the sensitivity of cell lines to sera from animals with CNS pathology indicates its potential for further detailed development as a biosensor test system.

Indexed as

AgingBiosensing TechniquesCentral Nervous System NeoplasmsGliomaAnimalsBiomarkers, TumorCell Line, TumorHumansNeurilemmomaRatsRats, WistarS100 Calcium Binding Protein beta SubunitSOXB1 Transcription FactorsBiomarkers, TumorS100b protein, ratS100 Calcium Binding Protein beta SubunitSOXB1 Transcription Factors11-9-2 glioblastomabiosensor test systemblood serumNGUK-1 neuromapathology of aging

Identifiers

PMID42047723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.