Evidence map›Paper›PMID 42047397›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2026

Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High-Sensitivity C-Reactive Protein Levels.

Katharina Mueller, Alex Messner, Johannes Nairz, Ursula Kiechl-Kohlendorfer, Michael Knoflach, Sophia Zollner-Kiechl, Early Vascular Ageing in the Youth study group

Abstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katharina MuellerVASCage, Centre on Clinical Stroke Research, Innsbruck, Austria.ORCID https://orcid.org/0009-0006-8255-6257
Alex MessnerVASCage, Centre on Clinical Stroke Research, Innsbruck, Austria.
Johannes NairzVASCage, Centre on Clinical Stroke Research, Innsbruck, Austria.
Ursula Kiechl-KohlendorferDepartment of Paediatrics II, Medical University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0000-0003-0433-6196
Michael KnoflachVASCage, Centre on Clinical Stroke Research, Innsbruck, Austria.
Sophia Zollner-KiechlVASCage, Centre on Clinical Stroke Research, Innsbruck, Austria.ORCID https://orcid.org/0000-0001-8856-5986
Early Vascular Ageing in the Youth study group

Funding

VASCage-Centre on Clinical Stroke Research 898252
6 · The paper itself

Abstract

aimThis Prospective, Community-Based Cohort Study Investigated Cardiovascular Health and Its Association With Low-Grade Inflammation in Adolescents.

methodsData were collected by specially trained medical staff from 1379 Austrian adolescents aged 14-19 years from 3 February 2021 to 28 February 2023. These included a self-report, assisted questionnaire and structured interview. Cardiovascular health was assessed using the American Heart Association's Life's Essential 8 score and chronic low-grade inflammation was measured by high-sensitivity C-reactive protein levels. Associations were analysed using multivariable linear regression.

resultsThe average Life's Essential 8 score suggested 75.0% adherence to ideal cardiovascular health recommendations and 68.2% of the cohort had moderate total cardiovascular health scores. High-sensitivity C-reactive protein levels indicated that 66.5% of the adolescents had a low risk of cardiovascular disease. These levels were associated with the total Life's Essential 8 scores (p < 0.001), as well as age (p < 0.001), female sex (p < 0.001), dietary habits (p = 0.029), active smoking (p < 0.001), higher body mass index z-scores (p < 0.001), and oral hormonal contraceptive use (p < 0.001).

conclusionOverall, cardiovascular health was moderate and showed an inverse relationship with high-sensitivity C-reactive protein levels. Improved dietary habits, appropriate physical activity and not using tobacco may help to reduce systemic inflammation and cardiovascular risks.

Indexed as

Cardiovascular DiseasesC-Reactive ProteinAdolescentAustriaFemaleHumansInflammationMaleProspective StudiesVascular HealthYoung AdultC-Reactive Proteincardiovascular riskdietary habitshigh‐sensitive C‐reactive proteinlife's essential 8 scorelow grade inflammation

Identifiers

PMID42047397
PMCPMC13371824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.