Evidence map›Paper›PMID 42047250›Full record

ArticleACS chemical biology2026

Butuanimides, Fatty Acid Synthesis-Inhibiting Antibiotics from Symbiotic Bacteria.

Bailey W Miller, Albebson L Lim, Jeannie Bailey, Mark Jeremiah B Cleofas, Noel Lacerna, Marvin A Altamia, Jared T Seale, Jose Miguel D Robes, Hiroaki Naka, Colin Manoil and 3 more

Abstract read
In one paragraph

Article in ACS chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bailey W MillerDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0003-3204-3235
Albebson L LimDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0001-9972-3425
Jeannie BaileyDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, United States.
Mark Jeremiah B CleofasThe Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines.ORCID 0009-0009-2163-5893
Noel LacernaThe Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines.
Marvin A AltamiaThe Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines.
Jared T SealeDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0003-3505-4861
Jose Miguel D RobesThe Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines.ORCID 0000-0002-5593-712X
Hiroaki NakaDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
Colin ManoilDepartment of Genome Sciences, University of Washington, Seattle, Washington 98195, United States.
Margo G HaygoodDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0001-5277-9544
Eric W SchmidtDepartment of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.ORCID 0000-0001-5839-694X
Gisela P ConcepcionThe Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines.ORCID 0000-0002-2216-5637

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Diverse Drug Lead Compounds from Bacterial Symbionts in Philippine MollusksU19TW008163 · FIC · UNIVERSITY OF UTAH · PI HAYGOOD, MARGO GENEVIEVE · 2014 to 2018
$5.2M
Microbial Ecology-Guided Discovery of Antibacterial DrugsR01AI162943 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Eric W Schmidt · 2022 to 2026
$3.2M
FIC NIH HHS U19 TW008163NIAID NIH HHS R01 AI162943NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

With the ongoing antibiotic drug resistance crisis, new molecules with new mechanisms of action are essential. Here, we characterized quorum sensing-regulated butuanimides from symbiotic γ-proteobacteria,

Indexed as

Anti-Bacterial AgentsFatty AcidsFatty Acid Synthesis InhibitorsAcetyl-CoA CarboxylaseHumansSymbiosisAcetyl-CoA CarboxylaseAnti-Bacterial AgentsFatty AcidsFatty Acid Synthesis Inhibitors

Identifiers

PMID42047250
PMCPMC13151354

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.