Evidence map›Paper›PMID 42047114›Full record

ArticleJournal of hypertension2026

Association between high likelihood of obstructive sleep apnea and masked hypertension: findings from the Jackson heart and coronary artery risk development in young adults studies.

Marwah Abdalla, Bharat Poudel, Swati Sakhuja, Brandon Fernandez-Sedano, Michelle L David, Sumayya Shurovi, Mark J Butler, Shakia T Hardy, Chandra L Jackson, Dayna A Johnson and 13 more

Abstract read
In one paragraph

Article in Journal of hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Marwah AbdallaDepartment of Medicine, Columbia University Irving Medical Center, New York, New York.
Bharat PoudelDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Swati SakhujaDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Brandon Fernandez-SedanoDepartment of Medicine, Columbia University Irving Medical Center, New York, New York.
Michelle L DavidDepartment of Medicine, Columbia University Irving Medical Center, New York, New York.
Sumayya ShuroviDepartment of Medicine, Columbia University Irving Medical Center, New York, New York.
Mark J ButlerInstitute of Health System Science, Northwell Health, New York, New York.
Shakia T HardyDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill.
Chandra L JacksonEpidemiology Branch, Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.
Dayna A JohnsonDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
See Ling LoyDepartment of Reproductive Medicine, KK Women's and Children's Hospital, Singapore.
Gbenga OgedegbeInstitute for Excellence in Health Equity, NYU Langone Health, New York, New York.
Joseph E SchwartzDepartment of Medicine, Columbia University Irving Medical Center, New York, New York.
James M ShikanyDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Daichi ShimboDepartment of Medicine, Columbia University Irving Medical Center, New York, New York.
Mario SimsDepartment of Social Medicine, Population and Public Health, School of Medicine University of California Riverside, Riverside, California.
Tanya M SpruillInstitute for Excellence in Health Equity, NYU Langone Health, New York, New York.
Carmen D TekweDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington, Indiana.
S Justin ThomasDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama.
Natasha J WilliamsInstitute for Excellence in Health Equity, NYU Langone Health, New York, New York.
Roger S ZohDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington, Indiana.
Susan RedlineDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.

Funding

Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Automated clinic blood pressure assessment and detection of white coat and masked hypertension study in African AmericansR01HL146636 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABDALLA, MARWAH · 2020 to 2025
$3.8M
NHLBI NIH HHS R01 HL117323NHLBI NIH HHS R01 HL146636
6 · The paper itself

Abstract

objectiveMasked hypertension [nonhigh office blood pressure (BP) and high out-of-office BP] is associated with cardiovascular risk. Obstructive sleep apnea (OSA) is associated with high office BP, but few data exist on its association with masked hypertension, especially in Black adults who have a high prevalence of both conditions.

methodsWe analyzed pooled data from 1078 Black adults, 713 in the Jackson Heart Study and 365 in the Coronary Artery Risk Development in Young Adults study, with office BP less than 140/90 mmHg, who completed 24-h ambulatory BP monitoring. Masked hypertension was defined as mean awake BP at least 135/85 mmHg, asleep BP at least 120/70 mmHg, or 24-h BP at least 130/80 mmHg. A high likelihood of OSA was defined using sleep questionnaires and physical measurements. Poisson regression was used to estimate prevalence ratios, adjusting for demographics, lifestyle behaviors, and comorbidities. Analyses were stratified by antihypertensive medication use.

resultsOverall, 34% of participants had a high likelihood of OSA; 53.3% had masked hypertension. Among participants not taking antihypertensive medication ( n  = 505), adjusted prevalence ratios comparing those with versus without a high likelihood of OSA were 1.31 [95% confidence interval (CI) 1.06-1.61], 0.88 (95% CI 0.59-1.29), 1.37 (95% CI 1.09-1.73), and 1.35 (95% CI 1.00-1.83) for any, awake, asleep, and 24-h masked hypertension. Among those taking antihypertensive medication ( n  = 573), the adjusted prevalence ratios were 1.15 (95% CI 0.99-1.32), 1.04 (95% CI 0.83-1.31), 1.14 (95% CI 0.97-1.33), and 1.19 (95% CI 0.96-1.47), respectively.

conclusionA high likelihood of OSA was associated with a higher prevalence of masked hypertension among participants not taking antihypertensive medication.

Indexed as

Masked HypertensionSleep Apnea, ObstructiveAdultBlood PressureBlood Pressure Monitoring, AmbulatoryFemaleHumansMalePrevalenceRisk FactorsYoung Adult24-hour ambulatory blood pressuremasked hypertensionobstructive sleep apnea

Identifiers

PMID42047114
PMCPMC13236034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.