Evidence map›Paper›PMID 42046875›Full record

ArticleJournal of Zhejiang University. Science. B2026

Infra-slow body-surface potentials show a group-level association with thyroid cancer.

Bohan Deng, Ruili Zhang, Yuxuan Liu, Jinglao Lin, Shicong Gui, Xihao Wei, Yin Cheng, Li Zheng, Shaohua Hu, Pingping Lyu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bohan DengCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Ruili ZhangDepartment of Nursing, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
Yuxuan LiuCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Jinglao LinCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Shicong GuiCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Xihao WeiCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
Yin ChengDepartment of Nursing, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
Li ZhengDepartment of Nursing, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
Shaohua HuDepartment of Nursing, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
Pingping LyuDepartment of Nursing, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
Yubo LiCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China. lilinear@zju.edu.cn.
Huafen WangDepartment of Nursing, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China. 2185015@zju.edu.cn.

Funding

the 2025 Beilun District Health Science and Technology Plan Project 2025BLWSZD001
6 · The paper itself

Abstract

Thyroid cancer is a common malignancy with broad systemic endocrine and metabolic effects (Hammond et al., 2024). Regarding diagnostics, if infra-slow body-surface potential (BSP) features reflect a systemic state, then this type of cancer is a reasonable clinical test case. Prior electrodermal work has focused on faster transients above 0.5 Hz (Boucsein, 2012; Posada-Quintero and Chon, 2020), and task-state skin potential abnormalities have been shown to distinguish mood disorders from healthy controls (Lyu et al., 2024). We concentrated on an infra-slow band from 0.025 to 0.2 Hz, called Band 1 herein. We evaluated whether infra-slow features carry reproducible group-level information when artifacts are explicitly controlled, with one pre-specified primary endpoint. "Separable" here means a group-level statistical difference, not individual-level diagnosis. In a cohort of 321 cancer patients, Band 1 energy showed a clear group-level association with thyroid cancer, which persisted after automated quality control (QC) and under stricter artifact-removal settings.

Indexed as

Thyroid NeoplasmsAdultAgedArtifactsFemaleGalvanic Skin ResponseHumansMaleMiddle Aged

Identifiers

PMID42046875
PMCPMC13121882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.