Evidence map›Paper›PMID 42046869›Full record

ReviewJournal of Zhejiang University. Science. B2026

Neuroscientific therapies for subjective tinnitus.

Peng Liu, Xinmiao Xue, Zhixin Zhang, Hanwen Zhou, Cong Xu, Lijun Zhang, Zhen Li, Yongqing Zhou, Shanwei Song, Yameng Tian and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of Zhejiang University. Science. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peng LiuDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China.
Xinmiao XueDepartment of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China.
Zhixin ZhangDepartment of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China.
Hanwen ZhouDepartment of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China.
Cong XuDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China.
Lijun ZhangDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China.
Zhen LiDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China.
Yongqing ZhouDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China.
Shanwei SongSchool of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300380, China.
Yameng TianDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China.
Fangyuan WangDepartment of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China. fangyuanwang05@163.com.
Xiaoming LiDepartment of Otolaryngology, Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050011, China. xmlmo@126.com.
Shiming YangDepartment of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China. shm_yang@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinnitus, a prevalent auditory symptom, can significantly impair quality of life, yet no definitive pharmacological interventions exist despite extensive ongoing research into its pathophysiology and treatments. The advent of biomedical engineering has introduced neuromodulation as a pivotal therapeutic approach alongside conventional strategies such as pharmacotherapy and surgery. Through the deployment of invasive and non-invasive techniques, using various modalities including magnetic, electronic, and optical means, neuromodulation aims to regulate neural functions. This has not only led to the refinement of fundamental theories but has also enhanced the optimization of clinical applications. As an emerging and promising intervention, neuromodulation enriches the toolkit available for basic neuroscience inquiry and broadens the spectrum of clinical therapies for conditions affecting the central nervous system, including tinnitus. In this paper, we succinctly review the current understanding of tinnitus mechanisms, discuss the features of diverse neuromodulation technologies, explore their application in tinnitus management, and contemplate prospects for their development in treating tinnitus.

Indexed as

TinnitusAnimalsElectric Stimulation TherapyHumansTranscranial Magnetic StimulationElectrical stimulationLight stimulationMagnetic stimulationNeuromodulationTinnitus

Identifiers

PMID42046869
PMCPMC13121886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.