Evidence map›Paper›PMID 42046864›Full record

ArticleJournal of agricultural and food chemistry2026

Genotype and Agronomic Management Interactions Shape the Accumulation of Immunogenic and Toxic Gluten Peptides in Durum Wheat.

Giovanni Caccialupi, Leonardo Cicala, Justyna Milc, Alessandro Ulrici, Fatma Boukid, Arnaldo Dossena, Sara Graziano, Barbara Prandi, Giovanna Visioli, Nelson Marmiroli and 4 more

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giovanni CaccialupiDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, Pad. Besta, Reggio Emilia 42122, Italy.ORCID 0000-0001-7186-9297
Leonardo CicalaDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, Pad. Besta, Reggio Emilia 42122, Italy.
Justyna MilcDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, Pad. Besta, Reggio Emilia 42122, Italy.
Alessandro UlriciDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, Pad. Besta, Reggio Emilia 42122, Italy.
Fatma BoukidDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.ORCID 0000-0002-8688-5721
Arnaldo DossenaDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.
Sara GrazianoDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.
Barbara PrandiDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.ORCID 0000-0003-4444-0676
Giovanna VisioliDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.
Nelson MarmiroliDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.ORCID 0000-0001-9261-4699
Mariolina GullìDepartment of Chemistry, Life Sciences and Environmental Sustainability, Centre SITEIA. PARMA, University of Parma, Parma 43124, Italy.ORCID 0000-0001-8326-4965
Pasquale De VitaResearch Centre for Cereal and Industrial Crops, CREA-CI, Foggia 71122, Italy.
Nicola PecchioniDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, Pad. Besta, Reggio Emilia 42122, Italy.
Enrico FranciaDepartment of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, Pad. Besta, Reggio Emilia 42122, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there is growing interest in wheat-based products with a reduced digestive impact. We investigated whether agronomic management could modulate the accumulation of immunogenic peptides in durum wheat by using two multifactorial field trials. In the first trial, immunogenic peptide levels were influenced by genotype and by its interaction with nitrogen supply and sowing density, indicating that management effects are highly genotype dependent. In the second trial, the sowing date and fertilization regime affected immunogenic peptide accumulation, with the sowing date being the main driver. Spring sowing reduced the grain yield and increased grain protein and immunogenic peptide levels compared with fall sowing. Overall, these results support the adoption of genotype-specific management strategies to reduce immunogenic peptide accumulation while maintaining a yield in durum wheat.

Indexed as

GlutensPeptidesTriticumGenotypeSeasonsSeedsGlutensPeptidesagronomic managementdurum wheatgluten proteinimmunogenic peptides

Identifiers

PMID42046864
PMCPMC13154179

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.