ArticleInternational journal of endocrinology2026
Quantitative MRI Assessment of Orbital Structures in Radioactive Iodine-131 Therapy for Inactive Graves' Ophthalmopathy.
Article in International journal of endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Quantitative MRI Assessment of Orbital Structures in Radioactive Iodine-131 Therapy for Inactive Graves' Ophthalmopathy.International journal of endocrinology · 2026Article
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Abstract
Objective: The understanding regarding the role of orbital magnetic resonance imaging (MRI) in predicting the prognosis of radioactive iodine-131 (I-131) therapy for patients with inactive Graves' ophthalmopathy (GO) is limited. Therefore, this study aimed to explore the application of MRI quantitative measurements of orbital structures in radioactive I-131 therapy for inactive GO. Methods: This retrospective study included 41 patients (82 eyes) diagnosed with GO at Anhui Medical University Affiliated Fuyang Hospital and Anhui Medical University First Affiliated Hospital from January 2022 to October 2025 as the GO group, and 32 patients (64 eyes) with Graves' disease (GD) who were matched with the GO group in terms of gender and age were selected as the GD group. All patients were treated with radioactive I-131 using the calculated dose method. MRI conventional images and readout segmentation of long variable echo-trains diffusion-weighted imaging (RESOLVE DWI) were performed before and after I-131 treatment, as well as the thyroid technetium ( Results: Before radioactive I-131 treatment, there were statistically significant differences in the average values of apparent diffusion coefficient (ADC) of the lacrimal gland and the long diameter of the transverse lacrimal gland between the GO group and the GD group ( Conclusion: In patients with GO, lacrimal gland protrusion, MRI lacrimal gland length and area, and mean lacrimal gland ADC value may be reliable imaging indicators for evaluating the I-131 treatment.
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