Evidence map›Paper›PMID 42046736›Full record

ReviewInternational journal of nanomedicine2026

Advancements in Nanomedicine for Precision Management of Lymphoma: Mechanisms, Diagnostics, and Therapeutic Strategies.

Rong Wang, Zhongsong Zhang, Qi Wang, Panpan Gu, Yang Yang, Bing Wang, Yuanyin Teng

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rong Wang *School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan Province, 610550, People's Republic of China.
Zhongsong Zhang *School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan Province, 610550, People's Republic of China.ORCID 0009-0009-9465-6425
Qi WangSchool of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan Province, 610550, People's Republic of China.ORCID 0009-0000-6929-2871
Panpan GuInstitutes of Biomedical Sciences, Fudan University, Shanghai, Shanghai Municipality, 200032, People's Republic of China.
Yang YangDepartment of Cardiology, International School of Medicine, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, Yiwu, Zhejiang Province, 322000, People's Republic of China.ORCID 0009-0005-1863-8103
Bing WangDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, 510000, People's Republic of China.
Yuanyin TengInstitute of Hematology, Zhejiang University, Hangzhou, Zhejiang Province, 310003, People's Republic of China.ORCID 0009-0003-5331-7220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoma is a heterogeneous malignancy originating from the lymphatic and hematopoietic systems. Traditional diagnostic and therapeutic approaches face significant limitations due to the complexity, dissemination, and drug resistance associated with lymphoma. Thus, novel approaches are required for precise management and treatment. Recently, advances in nanotechnology have provided new possibilities for lymphoma therapy, particularly through interdisciplinary research combining materials science and biomedicine, thus offering promising strategies for precision treatment. This review systematically summarizes recent advancements in nanomedicine for lymphoma management. First, it introduces mechanisms of nanotechnological interventions, emphasizing lymphoma's pathological features. Next, cutting-edge diagnostic applications, including extracellular vesicle detection, high-sensitivity nucleic acid biomarker sensing, and multimodal imaging, are highlighted. Additionally, emerging therapeutic strategies such as integrated nanoplatforms combining diagnostics, treatment, and real-time monitoring are discussed. Examples include optimized mRNA vaccine delivery, enhanced chimeric antigen receptor (CAR) T-cell therapy, bispecific nanoparticle systems, and combination gene/chemotherapy approaches. Finally, this review outlines the challenges associated with clinical translation and suggests future directions for intelligent adaptive nanomedicine, emphasizing its potential to significantly advance lymphoma diagnosis and therapeutic paradigms.

Indexed as

LymphomaNanomedicinePrecision MedicineAnimalsDrug Delivery SystemsHumansTheranostic NanomedicineCAR-T-cell therapydiagnostic drug deliverylymphomananomedicineprecision medicinetheranostics

Identifiers

PMID42046736
PMCPMC13110737

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.