Evidence map›Paper›PMID 42046703›Full record

ArticleInternational medical case reports journal2026

Spontaneous Recovery from Hepatitis A-Induced Acute Liver Failure in a Child: A Rare Case Report from Hargeisa Group Hospital, Somaliland.

Khadar Jama Ibrahim, Abdisamed Mohamoud H Ali, Mohamoud Jimale Dirir, Sadam Ismail Ahmed

Abstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Khadar Jama IbrahimDepartment of Emergency, Hargeisa Group Hospital, Hargeisa, Somaliland.
Abdisamed Mohamoud H AliDepartment of Emergency, Hargeisa Group Hospital, Hargeisa, Somaliland.
Mohamoud Jimale DirirDepartment of Emergency, Hargeisa Group Hospital, Hargeisa, Somaliland.
Sadam Ismail AhmedFaculty of Medicine and Health Science, University of Burao, Burao, Somaliland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hepatitis A-induced acute liver failure (ALF) is a rare but leading cause of pediatric ALF in developing countries. ALF is defined as severe acute liver injury with coagulopathy and hepatic encephalopathy occurring within 26 weeks of symptom onset in patients without pre-existing chronic liver disease. It carries high mortality, accounting for approximately 8% of liver transplants worldwide, with reported survival rates ranging from 30-60% in the absence of transplantation. Fewer than 1% of patients with hepatitis A progress to ALF. Case Presentation: A 5-year-old girl from Wajaale, Somaliland, presented with fever, jaundice, and altered consciousness. She also developed hematemesis secondary to severe coagulopathy (INR 4.0), with no evidence of esophageal varices. Laboratory evaluation revealed markedly elevated transaminases and hyperbilirubinemia. HAV IgM was positive. Supportive therapy with lactulose, neomycin, vitamin K, and nutritional support resulted in full clinical and biochemical recovery without the need for liver transplantation. Conclusion: This case demonstrates that spontaneous recovery from HAV-induced ALF is possible with timely supportive care, even in resource-limited settings where monitoring and grading of encephalopathy are vital. It underscores the public health importance of strengthening supportive care protocols and implementing universal HAV vaccination to prevent these high-mortality emergencies.

Indexed as

acute liver failurehepatitis apediatricspublic healthSomalilandspontaneous recovery

Identifiers

PMID42046703
PMCPMC13110806

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