Evidence map›Paper›PMID 42046652›Full record

ArticleJournal of rehabilitation and assistive technologies engineering

Comparing the effect of off-loading knee brace with and without local muscle vibration on clinical and biomechanical outcomes in patients with medial knee osteoarthritis: A randomized clinical trial.

Mahsa Zangi, Mahmood Bahramizadeh, Mobina Khosravi, Farzam Farahmand, Mokhtar Arazpour, Koorosh Barati

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Article in Journal of rehabilitation and assistive technologies engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mahsa ZangiDepartment of Orthotics and Prosthetics, University of Social Welfare and Rehabilitation, Tehran, Iran.ORCID https://orcid.org/0009-0008-0248-6434
Mahmood BahramizadehDepartment of Orthotics and Prosthetics, University of Social Welfare and Rehabilitation, Tehran, Iran.
Mobina KhosraviPhysiotherapy Research Center, Department of Orthotics and Prosthetics, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-2947-0834
Farzam FarahmandBiomechanics, Sharif University of Technology, Tehran, Iran.
Mokhtar ArazpourDepartment of Orthotics and Prosthetics, University of Social Welfare and Rehabilitation, Tehran, Iran.
Koorosh BaratiDepartment of Orthotics and Prosthetics, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Medial knee osteoarthritis (KOA) is a prevalent degenerative joint disease causing pain and functional impairment. Off-loading knee braces reduce pain but may decrease muscle activity, leading to weakness. Integrating local muscle vibration (LMV) into off-loading braces may enhance muscle activation and clinical outcomes. Objective: To design a portable LMV system synchronized with gait phases and compare its efficacy to a conventional off-loading brace in patients with medial KOA. Methods: In this randomized clinical trial, 16 patients with medial KOA were assigned to either an LMV-equipped off-loading brace group or a conventional brace group for 4 weeks. Clinical outcomes (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC], Visual Analog Scale [VAS]) and biomechanical parameters (knee adduction moment [KAM1, KAM2], impulse, range of motion [ROM], cadence, stride length) were assessed pre- and post-intervention using validated questionnaires and a motion analysis system. Results: The LMV-equipped brace group demonstrated a significantly greater reduction in KAM impulse (-24.79% vs. -7.68%, p=0.050) and improved knee ROM (p=0.048) compared to the conventional brace group. Significant improvements in WOMAC (p=0.001) and VAS (p=0.011) scores were observed in the LMV group, indicating enhanced functional status and pain relief. Conclusion: The LMV-equipped off-loading brace provides superior biomechanical (KAM impulse, ROM) and clinical outcomes compared to conventional braces, offering a promising intervention for medial KOA.

Indexed as

knee adduction momentknee osteoarthritislocal muscle vibrationoff-loading knee bracepain management

Identifiers

PMID42046652
PMCPMC13110341

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.