Evidence map›Paper›PMID 42046211›Full record

ArticleNephrology (Carlton, Vic.)2026

Chronic Kidney Disease-Associated Pruritus in Patients on Home Haemodialysis.

Kavana Krishna Nayak, Jing Xin Goh, Kamal Sud, Surjit Tarafdar, Linda Le Do, Nazim Bhimani, Girish Thunga, Ronald L Castelino

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In one paragraph

Article in Nephrology (Carlton, Vic.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kavana Krishna NayakSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0009-0008-1456-2828
Jing Xin GohSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0009-0002-4061-1722
Kamal SudSydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-7648-007X
Surjit TarafdarFaculty of Medicine, Western Sydney University, Sydney, New South Wales, Australia.
Linda Le DoSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Nazim BhimaniSydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0003-3995-4285
Girish ThungaDepartment of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.ORCID https://orcid.org/0000-0003-1257-969X
Ronald L CastelinoSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-5128-7115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimChronic kidney disease-associated pruritus is a common and distressing symptom in people with chronic kidney disease and is linked to increased mortality. Home haemodialysis is associated with a number of benefits compared to centre-based haemodialysis. However, the impact of chronic kidney disease-associated pruritus in patients receiving home haemodialysis on patient-reported outcomes such as symptom burden, quality of life, anxiety and depression and sleep disorders is not well understood. In this cross-sectional study on 59 patients on home haemodialysis, we aimed to determine the prevalence of chronic kidney disease-associated pruritus and its impact on patient-reported outcomes.

methodsThe 5-D itch scale and EQ-5D were used to measure itch severity and quality of life, respectively.

resultsThe prevalence of chronic kidney disease-associated pruritus was 31% (n = 18). Patients with chronic kidney disease-associated pruritus reported poorer quality of life compared to the non-pruritus group (0.760 vs. 1.00, p = 0.042). However, there was no significant association between pruritus severity and patient-reported outcomes, including quality of life.

conclusionThese findings highlight the complex relationship between pruritus and quality of life in patients on home haemodialysis and underscored the need for more extensive, longitudinal studies to better explore correlations between pruritus severity and patient-reported outcomes, with the view to improving pruritus management and enhancing clinical outcomes.

Indexed as

Hemodialysis, HomePruritusRenal Insufficiency, ChronicAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresPrevalenceQuality of LifeSeverity of Illness IndexSymptom Burdenhome haemodialysispatient reported outcome measurespruritusquality of lifesymptom burden

Identifiers

PMID42046211
PMCPMC13121874

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.