Evidence map›Paper›PMID 42046105›Full record

ArticleJournal of cardiothoracic surgery2026

Early oxygenator failure during cardiopulmonary bypass with preserved neurological outcome: a case report.

Madiha Khan, Saad Ahmed Naved, Muhammad Zameer Rajput, Muhammad Usman Ali Shah

Abstract readCase Reports
In one paragraph

Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madiha KhanDepartment of Anesthesia, Shifa International Hospitals Limited, H-8/4, Islamabad, Pakistan. madiha.k.94@gmail.com.
Saad Ahmed NavedDepartment of Anesthesia, Shifa International Hospitals Limited, H-8/4, Islamabad, Pakistan.
Muhammad Zameer RajputDepartment of Anesthesia, Shifa International Hospitals Limited, H-8/4, Islamabad, Pakistan.
Muhammad Usman Ali ShahDepartment of Cardiovascular and Thoracic surgery, Shifa International Hospitals Limited, H-8/4, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOxygenator failure during cardiopulmonary bypass (CPB) is a rare but potentially catastrophic intraoperative event that can result in sudden hypoxemia and neurological injury if not promptly recognized and managed. CASE PRESENTATION: We report the case of a 72-year-old man undergoing urgent on-pump coronary artery bypass grafting who developed early oxygenator failure within minutes of CPB initiation. The event was identified by progressive darkening of the arterial blood and a decline in pulse oximetry values. Immediate corrective measures included resuming lung ventilation with 100% oxygen, brief hypothermic circulatory arrest, and rapid oxygenator replacement. The duration of impaired oxygenation was brief, and the oxygenation parameters improved promptly following the intervention. The patient was extubated early in the intensive care unit and did not exhibit neurological deficits during recovery.

conclusionThis case highlights the importance of continuous clinical vigilance, early recognition of unexpected hypoxemia, and decisive team-based management to prevent adverse neurological outcomes during rare perfusion emergencies.

Indexed as

Cardiopulmonary BypassCoronary Artery BypassHypoxiaIntraoperative ComplicationsOxygenatorsAgedEquipment FailureHumansMaleCardiopulmonary bypassHypoxemiaOxygenator failure

Identifiers

PMID42046105
PMCPMC13261822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.