ArticleBMC pediatrics2026
Vitamin D status and intake in early school-aged children is tracking from pregnancy-the Swedish GraviD-Child study.
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05228925 (GraviD-child Follow-up of the Children´s Health, Growth and Development Within the GraviD-study), which is not on this map. Cited by 1 paper.
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GraviD-child Follow-up of the Children´s Health, Growth and Development Within the GraviD-study
Who cites it
1 citing paper in PubMed.
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe foetus depends on maternal vitamin D status during pregnancy, and the strong correlation between maternal and newborn vitamin D status is well established. However, the long-term tracking of vitamin D status and intake from pregnancy and to childhood remains largely unexplored. We aimed to evaluate vitamin D status and its determinants in early school-aged children, and to explore the tracking of vitamin D status and intake from pregnancy to childhood.
methodsThe Swedish GraviD-Child study includes data of vitamin D status and intake from the mothers first trimester of pregnancy to their children at age 8 years. Concentrations of 25-hydroxyvitamin D (25OHD) were analysed in the first and third trimesters and in children at age 8 years. Vitamin D intake from vitamin D-rich foods was reported in the third trimester, and in children at the ages 5 and 8 years. Candidate determinants of 25OHD concentrations in the children at age 8 years were collected through questionnaires and clinical assessments and analysed using multivariable linear regression. Associations between season-corrected 25OHD concentrations and vitamin D intake during pregnancy and childhood were investigated by Spearman correlations.
resultsAmong the 145 children included in the analysis, the mean (SD) 25OHD concentration at age 8 was 67.8 (15.6) nmol/L, with the majority (91.7%) having levels ≥ 50 nmol/L. The only statistically significant determinant of 25OHD concentrations at age 8 were season of blood sampling, with sampling during May to October being associated with higher 25OHD concentrations (p < 0.001). Positive correlations were observed between season-corrected 25OHD concentrations in mothers first trimester and in children at age 8 (rho = 0.2, p = 0.022). Reported vitamin D intake in the third trimester was positively correlated with intake in children at ages 5 (rho = 0.21, p = 0.017) and 8 years (rho = 0.19, p = 0.04), with intake at age 5 also positively correlated with intake at age 8 (rho = 0.41, p < 0.001).
conclusionAmong early school-aged children in Sweden with generally adequate vitamin D status, season is an important determinant. In addition, vitamin D status and intake seems to track from pregnancy to childhood.
trial registration(NCT05228925|| https://www.clinicaltrials.gov/ || Registration Date 2021–11-18).
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