Evidence map›Paper›PMID 42045509›Full record

ArticleEuropean radiology2026

Bowel ischemia detection on portal venous CT: multireader evaluation of dual-energy and photon-counting spectral imaging.

Fiona Mankertz, Josephine Berger, Nour Maalouf, Ulrich Schmid, Benedikt Stenzl, Reza Dehdab, Sebastian Werner, Andreas Brendlin, Saif Afat, Judith Herrmann

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Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Fiona MankertzDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany. fiona.mankertz@med.uni-tuebingen.de.ORCID http://orcid.org/0000-0002-7441-1406
Josephine BergerDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Nour MaaloufDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Ulrich SchmidDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Benedikt StenzlDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Reza DehdabDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Sebastian WernerDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Andreas BrendlinDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Saif AfatDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.
Judith HerrmannDepartment of Diagnostic and Interventional Radiology, University Hospital Tübingen, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the diagnostic performance of portal-venous (PV) blended CT images alone vs PV blended images supplemented with spectral reconstructions for detecting acute bowel ischemia, stratified by scanner platform (dual-energy CT [DECT] vs photon-counting CT [PCCT]). MATERIALS AND

methodsThis retrospective single-center, multireader, crossover diagnostic accuracy study compared PV blended images alone (image set A) with PV blended images supplemented by spectral reconstructions (image set B: 40-keV virtual monoenergetic images, iodine maps, and virtual non-contrast images) acquired on DECT and PCCT. The reference standard was a prespecified composite derived from surgical and index-hospitalization documentation. Diagnostic performance was analyzed using mixed-effects logistic models for accuracy, sensitivity, and specificity, cumulative link mixed models for 7-point suspicion scores, and ROC analyses using a multireader multicase framework.

resultsA total of 378 patients (mean age, 68.1 years ± 7.4, 206 men) were evaluated. 150/378 (39.7%) were ischemia-positive by the composite reference standard. Accuracy increased from 73% (95% CI: 68-77) with blended images to 86% (82-89) with spectral reconstructions (OR: 2.30; 95% CI: 1.70-3.10; p < 0.001). Sensitivity increased from 75% (68-82) to 87% (81-92) (p = 0.008) and specificity from 72% (65-78) to 86% (80-90) (p < 0.001). Mean AUC improved by 0.16 (95% CI: 0.12-0.20; p < 0.001). Effects were similar on DECT and PCCT (interaction p = 0.24).

conclusionAdding spectral reconstructions to PV blended images improved accuracy, sensitivity, specificity, and diagnostic confidence for bowel ischemia detection, without evidence of platform-specific effect modification. KEY POINTS: Question Can spectral reconstructions improve bowel ischemia detection on portal venous (PV) phase abdominal CT, and are these gains consistent across DECT and PCCT? Findings Adding spectral reconstructions to PV blended images improved diagnostic performance and agreement for bowel ischemia on abdominal CT, with comparable effects on DECT and PCCT. Clinical relevance Spectral reconstructions from a single PV acquisition may improve emergency abdominal CT interpretation for bowel ischemia without additional acquisitions or radiation.

Indexed as

IntestinesIschemiaPortal VeinTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedPhotonsRadiographic Image Interpretation, Computer-AssistedRadiography, Dual-Energy Scanned ProjectionReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityCross-over studiesIschemiaObserver variationRadiography (dual-energy scanned projection)Tomography (X-ray computed)

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.