Evidence map›Paper›PMID 42045027›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2026

[Dynamic changes and physiological regulation of common carotid artery blood flow during general anesthesia in elderly patients: a prospective study].

Xingyang Liu, Jinghan Wu, Chunyan Ye, E Wang, Hao Hu

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xingyang LiuDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Jinghan WuDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Chunyan YeDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
E WangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Hao HuDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.

Funding

Joint Fund Project of the National Natural Science Foundation of China U24A20230
6 · The paper itself

Abstract

objectivesTo explore the dynamic pattern and physiological regulation of common carotid artery (CCA) blood flow during general anesthesia in elderly patients.

methodsA total of 193 elderly patients undergoing abdominal surgery were prospectively enrolled. Respiratory and hemodynamic variables and anesthetic depth of the patients were recorded throughout the perioperative period. CCA blood flow was measured at predefined time points using vector flow imaging. Heart rate, mean arterial pressure, end-tidal carbon dioxide, and bispectral index were included in a linear mixed-effects model, with patient ID as a random effect, to explore the physiological determinants of intraoperative CCA blood flow.

resultsCCA blood flow showed clear stage-related changes during general anesthesia. The mixed-effects model explained 52.0% of the variation in CCA blood flow (adjusted

conclusionsIntraoperative cerebral perfusion is not maintained by blood pressure alone but influenced jointly by ventilation, hemodynamic status, and anesthetic depth. Recognizing and managing these factors may help optimize cerebral perfusion during surgery.

Indexed as

Anesthesia, GeneralCarotid Artery, CommonAgedAged, 80 and overBlood Flow VelocityFemaleGeriatric AnesthesiaHemodynamicsHumansMaleProspective StudiesRegional Blood Flowcerebral perfusioncommon carotid artery blood flowelderly patientsgeneral anesthesiavector flow imaging

Identifiers

PMID42045027
PMCPMC13120980

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.