ArticleStatistics in medicine2026
Delayed Exposures and Pre-Exposure Periods in Self-Controlled Case Series Studies.
Article in Statistics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Association between COVID-19 vaccination and sudden death in apparently healthy younger individuals: A population-based case-control study.PLoS medicine · 2026Article
- Risk of acute liver injury following the mRNA (BNT162b2) and inactivated (CoronaVac) COVID-19 vaccines.Journal of hepatology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A key assumption of the self-controlled case series (SCCS) method is that exposures should not depend on the event of interest. However, treatments such as vaccines may be deferred after an adverse health event. One suggestion to handle such delayed exposures is to include a pre-exposure window in the SCCS model. We study the impact of such adjustments and of exposure deferment on the SCCS relative incidence estimates. We obtain explicit results in a simplified setting, and investigate more realistic scenarios by simulation. We develop some practical recommendations for sensitivity analyses: when the delayed exposures remain within the observation period, no adjustment is needed. When exposures are delayed beyond the end of the observation period, an adjustment may be required. In some circumstances the SCCS model for event-dependent exposures should be used rather than the standard SCCS model. These options are illustrated with three practical examples.
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Registered trials
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