Evidence map›Paper›PMID 42044107›Full record

ArticleNeuroepidemiology2026

Prevalence of Essential Tremor among Greeks Aged 65 Years or Older: Results from the HELIAD Study.

Nikolaos Giagkou, Georgia Xiromerisiou, Mary Yannakoulia, Paraskevi Sakka, Georgios M Hadjigeorgiou, Efthimios Dardiotis, Mary H Kosmidis, Nikolaos Scarmeas, Elan D Louis

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Article in Neuroepidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nikolaos Giagkou1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Georgia XiromerisiouDepartment of Neurology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Mary YannakouliaDepartment of Nutrition and Dietetics, Harokopio University, Athens, Greece.
Paraskevi SakkaAthens Association of Alzheimer's Disease and Related Disorders, Marousi, Greece.
Georgios M HadjigeorgiouDepartment of Neurology, Medical School, University of Cyprus, Nicosia, Cyprus.
Efthimios DardiotisDepartment of Neurology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Mary H KosmidisLab of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Nikolaos Scarmeas1st Department of Neurology, Aiginition Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Elan D LouisDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA, elan.louis@utsouthwestern.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: The prevalence of essential tremor (ET) demonstrates substantial differences across study populations and has been assessed in more than 40 population-based studies, but never in Greece. We directly estimated the prevalence of ET in community-dwelling adults aged 65 years and older, which was the age group expected to have the highest prevalence.

methodsParticipants in a population-representative cohort aged ≥65 years underwent a neurological evaluation. ET was operationally defined as a Bain and Findley scale score ≥4 on the Archimedes' spirals drawn with the more affected arm, excluding alternative causes of tremor. In a subset of participants, we validated this against diagnoses of ET assigned based on videotaped neurological examination. Logistic regression models were performed to assess independent effects of age and sex on prevalence.

resultsA total of 172 of 1,926 participants were classified as having ET, corresponding to a crude prevalence of 8.9% (95% confidence interval [CI] = 7.7%, 10.2%). The prevalence of ET increased with increasing age (65-69: 6.4%; 70-74: 6.6%; 75-79: 12.1%; ≥80: 14.1%, X2 test, p < 0.001) and was higher in male than female participants (11.7% vs. 7.0%, X2 test, p < 0.001). Both age and sex were significant predictors of ET, when assessed simultaneously using logistic regression - odds ratio (95% CIs) = 1.07 (1.04, 1.10) and 1.54 (1.11, 2.12), respectively. DISCUSSION: Our study provides the first estimate of ET prevalence in Greece and shows that ET is highly prevalent as it affects 8.9% of Greeks aged ≥65. </p>.

Indexed as

EpidemiologyEssential tremorGreecePrevalenceTremor

Identifiers

PMID42044107
PMCPMC13309074

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