Evidence map›Paper›PMID 42044081›Full record

ArticleAudiology & neuro-otology2026

Audiometric Outcomes and Longitudinal Trends of Sequential Cochlear Implantation in Adults with Bilateral Deafness: A 20-Year Single-Center Study.

Sarek A Shen, Zahra N Sayyid, Nicholas S Andresen, Courtney Carver, Dawn D Marsiglia, Jennifer Yeagle, Charles Della Santina, Steve P Bowditch, Daniel Q Sun

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Article in Audiology & neuro-otology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Sarek A ShenDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA, sarek.shen@gmail.com.
Zahra N SayyidDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Nicholas S AndresenDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Courtney CarverDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dawn D MarsigliaDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jennifer YeagleDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Charles Della SantinaDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Steve P BowditchDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Daniel Q SunDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

RESEARCH TRAINING IN OTOLARYNGOLOGYT32DC000027 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CAREY, JOHN PATRICK · 1989 to 2023
$5.5M
NIDCD NIH HHS T32 DC000027
6 · The paper itself

Abstract

<p>Introduction: In this study, we examine the outcomes and trends of second-side cochlear implant (CI) in adults as measured by change in speech perception scores, with a focus on those meeting age requirements for Medicare.

methodsThis is a retrospective cohort study performed at a tertiary academic center. The investigation included adult patients with bilateral hearing loss receiving sequential, bilateral CI between 2001 and 2020. Bilateral speech perception scores under best aided conditions were compared following first- and second-side CI using Arizona Biomedical (AzBio) Sentence Test, Consonant-Nucleus-Consonant word (CNC-W), and Hearing in Noise Test (HINT). Individual changes in audiometric scores and trends in implant age and inter-implant interval were evaluated.

resultsA total of 162 individuals were included in this study. 50 patients with AzBio scores, 40 patients with HINT scores, and 72 patients with CNC-W scores demonstrated mean improvements of 11.8 (95% CI: [5.7-17.9]), 6.7 (95% CI: [0.4-13.7]), 12.0 (SD: 25.3), and 11.5 (95% CI: [7.3-15.7]) points, respectively, following second-sided CI. Patients aged 65 and older experienced similar magnitude of improvement as younger patients (t-tests: AzBio: 95% CI: [-16.7, 17.4]; HINT: 95% CI: [-34.6, 0.5]; CNC-W: 95% CI: [-10.7, 13.1]). Longer time interval between implants was associated with reduced improvement in CNC-W in the overall population (β: -2.9, 95% CI: [-5.5 to -1.2]) and the elderly population (β: -4.24, 95% CI: [-6.1 to -2.8]) specifically. Over time, there were no significant changes in age of CI-1 implant or audiometric scores after bilateral CI, but there was a decrease in inter-implant interval.

conclusionsIntervention with a second-sided cochlear implant was associated with improved speech recognition scores and this benefit extended to patients aged 65 and over. Decreased inter-implant interval is associated with an increase in improvement. </p>.

Indexed as

Cochlear ImplantationCochlear ImplantsHearing Loss, BilateralSpeech PerceptionAdultAgedAged, 80 and overAudiometryFemaleHumansLongitudinal StudiesMaleMiddle AgedRetrospective StudiesTreatment OutcomeCochlear implantImplant-implant intervalLongitudinal trendsMedicareSecond-side cochlear implantSpeech perception score

Identifiers

PMID42044081
PMCPMC13165502

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.