Evidence map›Paper›PMID 42043853›Full record

ArticleMicrobial genomics2026

bifidoAnnotator: fine-grained annotation of bifidobacterial glycoside hydrolases for human milk glycan utilization.

Nicholas Pucci, Daniel R Mende

Abstract read
In one paragraph

Article in Microbial genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicholas PucciDepartment of Medical Microbiology & Infectious Diseases, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands.
Daniel R MendeDepartment of Medical Microbiology & Infectious Diseases, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human milk glycan (HMG) metabolism, especially by bifidobacteria, is crucial for infant gut colonization and healthy microbiome development. Bifidobacterial species and even strains are highly variable in their ability and in their enzymatic repertoire for HMG metabolism. The enzymes involved in HMG metabolism often have many non-HMG-related homologues, necessitating fine-grained annotation for accurate assessment of bifidobacterial HMG metabolic capabilities. However, current annotation tools provide only broad glycoside hydrolase (GH) (sub)family classifications. Here, we present

Indexed as

BifidobacteriumGlycoside HydrolasesMilk, HumanMolecular Sequence AnnotationPolysaccharidesSoftwareBacterial ProteinsHumansBacterial ProteinsGlycoside HydrolasesPolysaccharidesbifidobacteriabioinformaticsgenome annotationglycoside hydrolase (GH)human milk glycan (HMG) metabolismmicrobiome

Identifiers

PMID42043853
PMCPMC13120772

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.