Evidence map›Paper›PMID 42043835›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

ROS Self-Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment.

Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar-Yun Ellen Poon, Hung-Wing Li

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Man Lung LeeDepartment of Chemistry, The Chinese University of Hong Kong, Hong Kong SAR, China.
Jack Chun Hin ChenSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Wai Wing ChengDepartment of Chemistry, The Chinese University of Hong Kong, Hong Kong SAR, China.
Kwan Yee LauSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hiu Yee KwanCentre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-6088-7323
Ngar-Yun Ellen PoonSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Hung-Wing LiDepartment of Chemistry, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID https://orcid.org/0000-0003-4840-1965

Funding

Chinese University of Hong KongHong Kong Research Grant Council
6 · The paper itself

Abstract

The immunosuppressive tumor microenvironment (TME) severely limits the clinical efficacy of immunotherapy, largely due to the prevalence of "cold tumors" with minimal T cell infiltration. To address this, we developed a reactive oxygen species (ROS) self-supplying nanoplatform (HA-PGMC) by in situ growing copper peroxide (CuO

Indexed as

chemodynamic therapycold‐to‐hot tumor reprogrammingfenton catalystimmune checkpoint blockadeimmunogenic cell death

Identifiers

PMID42043835
PMCPMC13335509

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.