Evidence map›Paper›PMID 42043642›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

Performance of large language models on the Japanese cardiovascular surgery board examination: a comparative analysis of eight contemporary AI models with educational implications.

Kentaro Kasa, Daisuke Yoshimaru, Hiroki Ohta, Takao Ohki, Hirotaka James Okano

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kentaro KasaDivision of Vascular Surgery, Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Daisuke YoshimaruDivision of Regenerative Medicine, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan.
Hiroki OhtaDivision of Regenerative Medicine, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan. hiroojikei@gmail.com.
Takao OhkiDivision of Vascular Surgery, Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Hirotaka James OkanoDivision of Regenerative Medicine, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan. hjokano@jikei.ac.jp.

Funding

JSPS KAKENHI JP24K11980
6 · The paper itself

Abstract

objectiveLarge language models (LLMs) have shown strong performance on medical licensing and specialty examinations, but their utility in cardiovascular surgery certification and education remains unknown.

methodsWe evaluated eight LLMs (GPT-5, GPT-4o [OpenAI], Gemini-2.5Pro, Gemini-2.0, Gemma-3 [12B] [Google DeepMind], Claude-4, Claude-3 [Anthropic], and Llama-4 [Scout] [Meta AI]) using their official application programming interfaces as of September 2025. Examination items were obtained from the Japanese Cardiovascular Surgery Board (2021-2024; 523 questions). Texts were extracted from PDFs, images converted to JPEGs, and each question presented with a standardized Japanese prompt. Models produced three responses per item; final answers were determined by majority voting. Accuracy with 95% confidence intervals was calculated, and pairwise comparisons performed using McNemar's test.

resultsAcross 523 items, GPT-5 achieved the highest accuracy (87.4%), followed by Gemini-2.5Pro (85.7%); their performance did not differ significantly. Claude-4 ranked third (80.3%), exceeding the passing threshold in some years. GPT-4o (65.6%) and Gemini-2.0 (58.5%) showed moderate accuracy, whereas Claude-3 (36.9%), Gemma-3 (40.9%), and Llama-4 (52.2%) scored lower. Pairwise testing confirmed a clear stratification: high (GPT-5, Gemini-2.5Pro), upper-intermediate (Claude-4), mid (GPT-4o, Gemini-2.0), and low (others). All models declined with image-based items, with top models reduced to around 70%. Accuracy remained stable across years, with GPT-5, Gemini-2.5Pro, and occasionally Claude-4, surpassing the pass threshold.

conclusionsSuccessive model generations, particularly GPT-5 and Gemini-2.5Pro, consistently achieved passing-level accuracy. These findings highlight substantial gains through model evolution and underscore the potential of LLMs as supplementary tools for specialty education, despite persistent limitations in image-based reasoning.

Indexed as

Cardiovascular Surgical ProceduresCertificationEducational MeasurementEducation, Medical, GraduateLarge Language ModelsSpecialty BoardsClinical CompetenceEast Asian PeopleGenerative Artificial IntelligenceHumansJapanArtificial intelligenceLarge language modelsVision language models

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.