ArticleArchives of gynecology and obstetrics2026
Unfavorably altered fibrin clot properties in women with unexplained infertility: association with pregnancy outcomes.
Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesOvarian stimulation (OS) and pregnancy were shown to be associated with a prothrombotic state. We sought to determine whether a positive pregnancy outcome is related to fibrin clot properties and thrombin generation in women with unexplained infertility (UI) after OS followed by intrauterine insemination (IUI).
methodsWe studied 70 women with UI, aged 30.7 ± 3.5 years, BMI 24.7 ± kg/m
resultsUI women had prolonged lag time (+ 10.0%) and lower thrombin generation reflected by ETP (-17.8%) and formed clots less permeable (- 20.8%; K
conclusionsWomen with UI display unfavorably modified fibrin clot properties, especially those with negative pregnancy outcomes, which suggests the impact of fibrin clot characteristics on treatment results.
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