Evidence map›Paper›PMID 42043220›Full record

ArticleViruses2026

Eye Health and Vision Function in Adults Aging with Well-Controlled HIV.

Alison G Abraham, Xinxing Guo, Srijana Lawa, Aleks Mihailovic, Michael W Plankey, Todd T Brown, Joseph B Margolick, Pradeep Ramulu, Seema Banerjee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alison G AbrahamDepartment of Epidemiology, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-6863-0565
Xinxing GuoDepartment of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0001-5628-1225
Srijana LawaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Aleks MihailovicDepartment of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-7550-5164
Michael W PlankeyDepartment of Medicine, Georgetown University Medical Center, Washington, DC 20057, USA.
Todd T BrownDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Joseph B MargolickDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Pradeep RamuluDepartment of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Seema BanerjeeDepartment of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-5158-7062

Funding

National Heart Lung and Blood Institute U01HL146201
6 · The paper itself

Abstract

Here, we describe vision health in aging adults living with HIV (PLWH) and comparable people without HIV (PWOH) from the MACS/WIHS Combined Cohort Study (MWCCS). PLWH and PWOH aged 60 years and older were recruited from Baltimore/Washington, DC, from September 2021 to September 2023. Exact matching and sample weights were used to create age-balanced comparisons. Visual impairment (VA worse than 20/40 after refraction or CS worse than 1.50 logCS in the better eye) and the presence of eye pathology were assessed. We studied 74 PLWH (97% virally suppressed) and 65 PWOH, aged 61 to 79 years, 36% Black, and 87% male. For PLWH and PWOH, distance VA impairment was noted in 4% vs. 1%, respectively, and uncorrected refractive error in 15% vs. 5%. More than half had signs of dry eye disease (63% for PLWH and 51% for PWOH). About half of PLWH had developed at least an early stage of cataract, compared to 20% of PWOH. Posterior chamber abnormalities were observed in 4% and 0%, and glaucomatous changes in 19% and 25% of PLWH and PWOH, respectively. The need for eyecare was high among this sample of PLWH with viral suppression and PWOH.

Indexed as

AgingHIV InfectionsVision DisordersVision, OcularAgedCohort StudiesEye DiseasesFemaleHumansMaleMiddle AgedVisual Acuityaging healtheye diseaseHIVvision loss

Identifiers

PMID42043220
PMCPMC13120128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.