Differential Effects of Phenanthrene and Its Chlorinated Congeners on Hormone Production and Mitochondrial Function in Ovarian Granulosa Cells.

Genevieve A Perono, Laiba Jamshed, Rohita Dutt, Reese S Cameron, James J Petrik, Philippe J Thomas, Alison C Holloway

Abstract read

In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Genevieve A PeronoDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0003-1816-3433

Laiba JamshedDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0002-8510-3740

Rohita DuttDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON L8S 4L8, Canada.

Reese S CameronDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON L8S 4L8, Canada.

James J PetrikDepartment of Biomedical Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0001-7102-637X

Philippe J ThomasWildlife and Landscape Science Directorate, National Wildlife Research Center, Environment and Climate Change Canada, Ottawa, ON K1A 0H3, Canada.

Alison C HollowayDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0002-4343-5325

Funding

CIHR 461152CIHR PJT 159651Natural Sciences and Engineering Research Council of Canada CGS-D

6 · The paper itself

Abstract

Halogenated derivatives of polycyclic aromatic hydrocarbons (PAHs), such as chlorinated PAHs (ClPAHs), are an emerging class of contaminants that are being detected in the environment as well as in wildlife and human populations. Previous studies have shown that chemical substitution of PAHs, including chlorination, may alter the toxicity of parent PAHs; however, whether chlorination affects their endocrine-disrupting potential remains unexplored. In this study, we examined the effects of phenanthrene (Phe), one of the most prevalent PAHs, and its chlorinated congeners, 9-chlorophenanthrene (9ClPhe) and 9,10-dichlorophenanthrene (9,10Cl

Indexed as

apoptosisautophagyClPAHendocrine disruptionmitochondriaovaryphenanthrenepolycyclic aromatic hydrocarbons (PAH)

Identifiers

PMID42043140

DOI10.3390/toxics14040313

PMCPMC13120344

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.