Evidence map›Paper›PMID 42043105›Full record

ArticleToxics2026

A High-Throughput, High-Content Analysis of Dopaminergic Neurodegeneration in

David Benson, Seth Currie, Jia-Sheng Wang, Lili Tang

Abstract read
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David BensonInterdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602, USA.ORCID 0009-0009-4354-612X
Seth CurrieInterdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-0047-1545
Jia-Sheng WangInterdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-8458-9187
Lili TangInterdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0001-5595-2875

Funding

U.S environmental protection agency 84045301
6 · The paper itself

Abstract

Dopaminergic neurodegeneration is a hallmark of Parkinson's disease (PD), and environmental contaminants have been implicated in disrupting dopaminergic pathways. However, practical in vivo workflows for rapid, standardized, and accessible assessment of dopaminergic neurotoxicity remain limited. In this study, we built on our laboratory's established high-throughput framework and implemented a high-content imaging workflow to quantify DA neurodegeneration in

Indexed as

Caenorhabditis elegansdopamine-dependent behaviordopaminergic neurotoxicityenvironmental pollutantshigh-content imaginghigh-throughputPFAS

Identifiers

PMID42043105
PMCPMC13120318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.