Evidence map›Paper›PMID 42042825›Full record

ArticleVaccines2026

Engineering a Modular PapMV Nanoparticle Vaccine: Comparative Efficacy of a Covalent and a Non-Covalent N-Antigen Vaccine Against Emerging SARS-CoV-2 Variants.

Léa-J Blanchette, Marilène Bolduc, Tekeleselassie Woldemariam, Mitra Yousefi, Henintsoa Rabezanahary, Santa-M Olivera-Ugarte, Caroline Garneau, Myriam Angers, Rong Shi, Louis Flamand and 5 more

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Léa-J BlanchetteCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.ORCID 0009-0001-5788-0921
Marilène BolducCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.
Tekeleselassie WoldemariamVacine and Infectious Disease Organization (VIDO), Department of Veterinary Microbiology, University of Saskatchewan, 120 Veterinary Road, Saskatoon, SK S7N 5E3, Canada.ORCID 0000-0001-6481-9136
Mitra YousefiMcGill Life Sciences Complex, Bellini Building, 3649 Promenade Sir-William-Osler, Montreal, PQ H3G 0B1, Canada.
Henintsoa RabezanaharyCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.
Santa-M Olivera-UgarteCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.ORCID 0000-0002-1229-8399
Caroline GarneauCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.
Myriam AngersCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.
Rong ShiInstitut de Biologie Intégrative et des Systèmes, Pavillon Eugène-Marchand, Université Laval, 1030 Avenue de la Médecine, Québec City, PQ G1V 0A6, Canada.
Louis FlamandCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.ORCID 0000-0001-5010-4586
Mariana BazCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.ORCID 0000-0002-1230-0735
Silvia VidalMcGill Life Sciences Complex, Bellini Building, 3649 Promenade Sir-William-Osler, Montreal, PQ H3G 0B1, Canada.
Darryl FalzaranoVacine and Infectious Disease Organization (VIDO), Department of Veterinary Microbiology, University of Saskatchewan, 120 Veterinary Road, Saskatoon, SK S7N 5E3, Canada.ORCID 0000-0002-8805-8068
Jean-François LemayCentre National en Électrochimie et en Technologies Environnementales Inc., 2263 Av. du Collège Porte 7, Shawinigan, PQ G9N 6V8, Canada.
Denis LeclercCentre de Recherche du CHU de Québec, Université Laval, Axe Immunology and Infectious Diseases, 2705 Boul Laurier, Québec City, PQ G1V 4G2, Canada.ORCID 0000-0002-9323-1638

Funding

CIHR 485777
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

nanoparticlePapaya Mosaic Virus (PapMV)SARS-CoV-2TLR7/8 agonistvaccine

Identifiers

PMID42042825
PMCPMC13120244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.