Evidence map›Paper›PMID 42042769›Full record

ReviewVaccines2026

Determinants of Maternal RSV Vaccination Uptake: A Narrative Review.

Aikaterini I Nikolaou, Alexandra Soldatou, Georgia-Christiana Grantzi, Vasileios Giapros, Fani Ladomenou

Abstract readReview
In one paragraph

Review in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aikaterini I NikolaouDepartment of Pediatrics, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.ORCID 0009-0006-9065-7971
Alexandra SoldatouDepartment of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, 15772 Athens, Greece.ORCID 0000-0001-9976-8383
Georgia-Christiana GrantziEvangelismos General Hospital, 10676 Athens, Greece.
Vasileios GiaprosNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.
Fani LadomenouDepartment of Pediatrics, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0002-1090-3698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal vaccination against respiratory syncytial virus (RSV) represents a major advance in early-life infection prevention. Although clinical efficacy and early real-world effectiveness are well established, sustained population-level impact depends on equitable uptake. This review synthesizes determinants influencing maternal RSV vaccination within the evolving dual-strategy landscape that includes both maternal vaccination and infant monoclonal antibody prophylaxis. A structured narrative review was conducted following PRISMA principles. PubMed/MEDLINE and Google Scholar were searched for studies published between January 2022 and February 2026. Eligible studies examined behavioral, interpersonal, structural, economic, and policy determinants of maternal RSV vaccination uptake, as well as early implementation and modelling evidence. Findings were integrated within a multilevel analytical framework. Maternal uptake is shaped by interacting determinants across individual, healthcare provider, and health system domains. Key drivers include perceived infant disease severity, vaccine safety confidence, perceived effectiveness, and prior antenatal vaccination behavior. Healthcare provider recommendation consistently emerges as the strongest facilitator. Coverage variability reflects differences in reimbursement, antenatal care integration, and national policy endorsement. The coexistence of maternal vaccination and infant monoclonal antibody strategies introduces additional comparative decision-making complexity. Early implementation data indicate heterogeneous uptake and socioeconomic gradients, while modelling demonstrates sensitivity to coverage, timing, epidemiology, and cost. Translating biological efficacy into sustained public health benefit requires coordinated behavioral, structural, and policy strategies, strong provider engagement, and context-sensitive implementation frameworks to ensure equitable coverage.

Indexed as

health equityhealth services accessibilitymaternal vaccinationmonoclonal antibodiespregnancyrespiratory syncytial virusvaccine hesitancyvaccine uptake

Identifiers

PMID42042769
PMCPMC13119929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.