Evidence map›Paper›PMID 42042682›Full record

ArticlePediatric reports2026

Long-Term Outcomes After Childhood Stroke.

Kerttu Kivisikk, Pilvi Ilves, Mairi Männamaa, Eve Õiglane-Shlik, Nigul Ilves, Norman Ilves, Inga Talvik, Dagmar Loorits, Pille Kool, Rael Laugesaar

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Article in Pediatric reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Kerttu KivisikkDepartment of Pediatrics, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.
Pilvi IlvesDepartment of Radiology, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.
Mairi MännamaaChildren's Clinic, Tartu University Hospital, 50406 Tartu, Estonia.ORCID 0000-0001-5234-6474
Eve Õiglane-ShlikDepartment of Pediatrics, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.
Nigul IlvesDepartment of Radiology, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.
Norman IlvesDepartment of Radiology, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.
Inga TalvikTallinn Children's Hospital, 13419 Tallinn, Estonia.
Dagmar LooritsRadiology Clinic, Tartu University Hospital, 50406 Tartu, Estonia.
Pille KoolDepartment of Radiology, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.
Rael LaugesaarDepartment of Pediatrics, Institute of Clinical Medicine, University of Tartu, 50406 Tartu, Estonia.ORCID 0000-0003-2145-0556

Funding

Estonian Research Council PRG1912
6 · The paper itself

Abstract

The aim of this study was to assess long-term outcomes in patients with different vascular types of childhood stroke.

methodsData for children with childhood stroke (aged 29 days to 18 years) were collected from the Estonian Pediatric Stroke Database. Outcomes (death, recurrent stroke, epilepsy, neurodevelopmental outcome by pediatric stroke outcome measure (PSOM)) were assessed at a minimum of two years after stroke.

resultsLong-term outcome data were available for 44 patients with childhood stroke (including three patients who died of stroke). According to the PSOM, based on gender, age, location of stroke and epilepsy, there were no differences in outcomes, but patients with a Pediatric NIH Stroke Scale (PedNIHSS) score of ≥6 had worse outcomes compared to patients with a score of <6. Children with arterial hemorrhagic stroke (AHS) were more likely to die, suffer from epilepsy and develop problems in the cognition/behavior PSOM subscale compared to children with arterial ischemic stroke (AIS). Combined poor outcomes (epilepsy, PSOM ≥ 1, recurrent stroke, mortality) occurred in 75% (33/44) of all patients with long-term outcome data.

conclusionsCombined poor outcomes occurred in 75% of the patients with childhood stroke. Patients with AHS showed higher mortality and worse long-term outcomes compared to patients with AIS in certain neurodevelopmental domains.

Indexed as

arterial ischemic strokecerebral venous sinus thrombosischildhood strokehemorrhagic strokeoutcome

Identifiers

PMID42042682
PMCPMC13118958

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