Evidence map›Paper›PMID 42042623›Full record

ReviewNeuroSci2026

Sustained Effects of Physiotherapy Interventions on Balance, Gait, and General Motor Function in Patients with Parkinson's Disease: A Systematic Review and Meta-Analysis.

Madela Hasani, Ilektra Sidiropoulou, Anna Christakou, Antonia Marazioti, Spyridon Konitsiotis, Epameinondas Lyros

Abstract readReview
In one paragraph

Review in NeuroSci, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Madela HasaniDepartment of Physiotherapy, School of Health Sciences, University of Peloponnese, 23100 Sparta, Greece.
Ilektra SidiropoulouDepartment of Physiotherapy, School of Health Sciences, University of Peloponnese, 23100 Sparta, Greece.
Anna ChristakouDepartment of Physiotherapy, School of Health Sciences, University of Peloponnese, 23100 Sparta, Greece.ORCID 0000-0001-6744-2979
Antonia MaraziotiDepartment of Physiotherapy, School of Health Sciences, University of Peloponnese, 23100 Sparta, Greece.
Spyridon KonitsiotisDepartment of Neurology, Medical School, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-5217-1317
Epameinondas LyrosDepartment of Physiotherapy, School of Health Sciences, University of Peloponnese, 23100 Sparta, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeBalance and gait problems pose a significant burden in Parkinson's disease (PD), and they are often poorly treated with levodopa. We intended to summarize evidence of mid- and long-term impact of various physiotherapeutic interventions (≥3 months post-intervention) on dynamic balance, gait, and general motor function in patients with PD.

methodA systematic search was conducted across the PubMed, Cochrane Library, and Scopus databases to identify controlled clinical trials on sustained effects of various exercise interventions in PD on the outcomes of interest (lasting ≥ 3 months after completion of the exercise program). We conducted meta-analyses on commonly used clinical measures of dynamic balance and gait ability, as well as on UPDRS-III scores using the Comprehensive Meta-Analysis Software (CMA).

resultsA total of 26 studies were included in meta-analyses, with a total of 1261 participants in the experimental and 989 participants in the control groups. Positive cumulative effects at the post-exercise follow-up (3 to 23 months) were shown in favor of the intervention group regarding balance (SMD = 0.512, 95% CI [0.240, 0.785],

conclusionsExercise interventions can improve balance and gait, as well as preserve the overall motor function in patients with PD, also in the mid- and long-term post-intervention periods.

Indexed as

balancegaitmotor functionParkinson’s-diseasephysiotherapyrehabilitation

Identifiers

PMID42042623
PMCPMC13119462

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.