ArticleJournal of fungi (Basel, Switzerland)2026
Kog1 Represses Lipid Accumulation in
Article in Journal of fungi (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Oleaginous microorganisms usually accumulate large amounts of lipids under nitrogen limitation and in a carbon-abundant environment. However, how cells sense changes in nitrogen and carbon levels in the culture medium remains a research hotspot. Previous studies have found that the target of rapamycin complex 1 (TORC1) plays a core role in lipid accumulation in oleaginous microorganisms. The results of the Kog1 (the member proteins of TORC1) knockout strain constructed earlier by our group showed that the Kog1 negatively regulated lipid accumulation in the oleaginous fungus
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