Evidence map›Paper›PMID 42042316›Full record

ArticleInfectious disease reports2026

Matrix-Dependent Sensitivity of Two Pan-Trematode PCR Assays for Detecting

Hagen Frickmann, Andreas Hahn, Kirsten Alexandra Eberhardt, Ulrike Loderstädt, Norbert Georg Schwarz, Ralf Matthias Hagen

Abstract read
In one paragraph

Article in Infectious disease reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Rapid and Sensitive Detection ofTropical medicine and infectious disease · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hagen FrickmannDepartment of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 22049 Hamburg, Germany.ORCID 0000-0002-8967-9528
Andreas HahnInstitute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.ORCID 0000-0002-5157-8369
Kirsten Alexandra EberhardtDepartment of Gastroenterology, Hepatology and Infectious Diseases, University Hospital and Medical Faculty of the Heinrich Heine University, 40225 Düsseldorf, Germany.ORCID 0000-0002-1002-0326
Ulrike LoderstädtInstitute of Infection Control and Infectious Diseases, University Medical Center Göttingen, 37075 Göttingen, Germany.
Norbert Georg SchwarzIndependent Researcher, 67459 Böhl-Iggelheim, Germany.
Ralf Matthias HagenDepartment of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56070 Koblenz, Germany.ORCID 0000-0003-4875-1519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsTwo previously described pan-trematode-specific real-time PCR assays were comparatively assessed using diagnostic samples containing DNA of either the

resultsOut of a total of 655 samples containing

conclusionsWhile the assessed pan-trematode PCR assays showed insufficient sensitivity as screening tools for blood plasma, blood serum, tissue, and urine samples from individuals with suspected schistosomiasis, they were sufficiently sensitive when applied to stool samples, in which substantial amounts of target DNA, as indicated by low Ct values in the

Indexed as

diagnostic accuracypan-trematode PCRSchistosoma haematobium complexSchistosoma mansoni complexschistosomiasistest comparison

Identifiers

PMID42042316
PMCPMC13116562

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.