Evidence map›Paper›PMID 42042295›Full record

ArticleJournal of functional biomaterials2026

Evaluation of Post-Processing Time's Influence on Biocompatibility of 3D-Printed Denture Base Resins.

Miruna Dinescu, Vlad Gabriel Vasilescu, Lucian Toma Ciocan, Bianca Voicu-Balasea, Ana Maria Cristina Țâncu, Alexandra Ripszky, Florin Miculescu, Sabina-Ana Răuță, Alexia-Ecaterina Cârstea, Mihaela Pantea and 1 more

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miruna DinescuDepartment of Prosthodontics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.ORCID 0009-0004-1872-9956
Vlad Gabriel VasilescuDepartment of Dental Prostheses Technology, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.ORCID 0000-0001-6251-833X
Lucian Toma CiocanDepartment of Dental Prostheses Technology, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.ORCID 0000-0002-0329-5102
Bianca Voicu-BalaseaDepartment of Biochemistry, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0009-0002-7073-3309
Ana Maria Cristina ȚâncuDepartment of Prosthodontics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.ORCID 0000-0001-9973-1759
Alexandra RipszkyDepartment of Biochemistry, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-4345-282X
Florin MiculescuFaculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-6757-5616
Sabina-Ana RăuțăDepartment of Dental Prostheses Technology, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.
Alexia-Ecaterina CârsteaDepartment of Dental Prostheses Technology, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.ORCID 0009-0006-2154-6135
Mihaela PanteaDepartment of Prosthodontics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.ORCID 0000-0003-2402-8772
Marina ImreDepartment of Prosthodontics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the continuous development of additive technologies and light-sensitive resins, the biological performance of 3D-printed resins is strongly dependent on photopolymerization efficiency and post-processing conditions. This study evaluated the effect of post-curing duration on the cellular response to two denture base resins using direct contact and indirect eluate-based pathways. Human gingival fibroblasts were assessed through viability, membrane integrity, nitric oxide production, fluorescence live/dead staining, and caspase-3/7 activity. As a result of contact between the cells and the surface interface of the specimen disks, reduced metabolic activity was noticed compared with the control under direct exposure, indicating cellular stress. Extended polymerization has been demonstrated to improve metabolic activity and reduce apoptotic signals for the V-Print dentbase resin, whereas FotoDent Denture presented a less uniform response under the same parameters. Therefore, for evaluating the cytotoxicity of light-sensitive resins, it is not sufficient to assess only the saliva-soluble substances released from the resin, such as residual monomers, but also the 3D printing parameters.

Indexed as

cytotoxicitydenture base resindigital light processinglight curingpost-processing

Identifiers

PMID42042295
PMCPMC13117374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.