Development and Ex Vivo Evaluation of a Thermoreversible Silver Nanoparticle-Loaded Gel as a Biocompatible Intracanal Medicament.

Shih-Min Hsia, Ming-Gene Tu, Wen-Hao Yang, Tong-Hong Wang, Yin-Hwa Shih, Tzong-Ming Shieh

Abstract read

In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shih-Min HsiaSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0003-2888-2618

Ming-Gene TuSchool of Dentistry, China Medical University, Taichung 404328, Taiwan.

Wen-Hao YangSchool of Dentistry, China Medical University, Taichung 404328, Taiwan.

Tong-Hong WangBioBank, Chang Gung Memorial Hospital at Linkou, Taoyuan 333423, Taiwan.ORCID 0000-0001-9248-9031

Yin-Hwa ShihDepartment of Healthcare Administration, Asia University, Taichung 413305, Taiwan.ORCID 0000-0003-0893-4185

Tzong-Ming ShiehSchool of Dentistry, China Medical University, Taichung 404328, Taiwan.ORCID 0000-0003-1759-9120

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inspired by their biocompatibility and thermoreversible gelation-transitioning from room temperature liquids to body temperature gels-Pluronic hydrogels were employed in this study to optimize intracanal penetration and ensure medicament stability. We developed a silver nanoparticle (AgNP)-loaded Pluronic gel (AgNPs-P-gel) as a biocompatible, easily removable intracanal medicament. Following PRILE 2021 guidelines, AgNPs-P-gels (F127/F68) were evaluated for gelation, AgNP release, and antibacterial activity against

Indexed as

biofilm removalcytotoxicityendodontic disinfectionintracanal medicamentsilver nanoparticlesthermoreversible gel

Identifiers

PMID42042287

DOI10.3390/jfb17040180

PMCPMC13117496

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.