Evidence map›Paper›PMID 42042280›Full record

ArticleJournal of functional biomaterials2026

Towards Sustainable Bone Grafting: Life Cycle Assessment of Donor Cadaver-Derived Allograft (BMG) Production Using a BMP-Preserving Approach.

Szidonia Krisztina Veress, Mihai Vlad Golu, Lajos Csönge, Bernadette Kerekes-Máthé, Melinda Székely, Bálint Botond Bögözi

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Szidonia Krisztina VeressDoctoral School of Medicine and Pharmacy, IOSUD, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania.ORCID 0009-0000-0261-5189
Mihai Vlad GoluDepartment of Oral and Maxilo-Facial Surgery, Faculty of Dentistry, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Str., 540142 Targu Mures, Romania.ORCID 0000-0001-8776-2654
Lajos CsöngeWest-Hungarian Regional Tissue Bank, Petz Aladár University Teaching Hospital, Vasvári P. u. 2-4., 9024 Győr, Hungary.
Bernadette Kerekes-MáthéDepartment of Teeth and Dental Arches Morphology, Faculty of Dentistry, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Str., 540142 Targu Mures, Romania.ORCID 0000-0001-9643-6383
Melinda SzékelyDepartment of Teeth and Dental Arches Morphology, Faculty of Dentistry, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Str., 540142 Targu Mures, Romania.ORCID 0000-0002-3998-0638
Bálint Botond BögöziDepartment of Oral and Maxilo-Facial Surgery, Faculty of Dentistry, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gheorghe Marinescu Str., 540142 Targu Mures, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesHealthcare activities contribute significantly to climate change and environmental pollution. The demand for bone grafting is increasing, and the biological properties of bone substitute materials are critically important. A methodology aimed at preserving BMPs may offer an opportunity to improve the biological properties of donor cadaver-derived bone grafts. The aim of this study was to conduct a life cycle assessment of the BMP-preserving approach used in allograft production in order to enhance the environmental sustainability of bone grafting.

methodsFollowing primary data collection at the West Hungarian Regional Tissue Bank, environmental impacts were assessed using the OpenLCA software and the ReCiPe v1.03 (2016) midpoint and endpoint impact categories. A sensitivity analysis was also conducted under six alternative scenarios to evaluate which changes would have the greatest beneficial effect on environmental impacts.

resultsThe greatest environmental impacts of allograft production were observed in the categories of material resources: metals and minerals, terrestrial ecotoxicity, and climate change. The climate change impact was 66.759 kg CO

conclusionsTransitioning to more sustainable energy sources (e.g., wind power) would substantially improve the environmental performance of allograft production. Further research is needed to identify more sustainable alternatives for the chemical agents used during processing.

Indexed as

allograftsbone graftingbone morphogenetic proteindental implantationdisability-adjusted life yearsorthopedic surgerysustainable development

Identifiers

PMID42042280
PMCPMC13117126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.