Evidence map›Paper›PMID 42042201›Full record

ArticleMarine drugs2026

Orally Administered Rhamnan Sulfate from

Keiichi Hiramoto, Masashi Imai, Masahiro Terasawa, Koji Suzuki

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Keiichi HiramotoFaculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Minamitamagaki-cho 3500-3, Suzuka 513-8670, Mie, Japan.
Masashi ImaiFaculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Minamitamagaki-cho 3500-3, Suzuka 513-8670, Mie, Japan.ORCID 0009-0006-9308-1701
Masahiro TerasawaFaculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Minamitamagaki-cho 3500-3, Suzuka 513-8670, Mie, Japan.ORCID 0000-0003-1250-1569
Koji SuzukiFaculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Minamitamagaki-cho 3500-3, Suzuka 513-8670, Mie, Japan.

Funding

This research was conducted with funding from a joint research project between Konan Chemical Manufacturing Co., Ltd. and Suzuka University of Medical Science. Research number 141
6 · The paper itself

Abstract

Tumor metastasis is closely associated with coagulation and inflammation, particularly via thrombin-PAR1 signaling. However, the potential of natural polysaccharides such as rhamnan sulfate (RS) to modulate these pathways and suppress metastasis remains unclear. We aimed to investigate the effects of orally administered RS derived from

Indexed as

Lung NeoplasmsMelanoma, ExperimentalAdministration, OralAnimalsAortaCell Line, TumorChlorophytaEdible SeaweedsMaleMiceMice, Inbred C57BLThrombinThrombinB16 melanoma cellsC57BL/6J miceEMTinflammationmetastasisMonostroma nitidumPAR1rhamnan sulfate

Identifiers

PMID42042201
PMCPMC13117711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.